Evidence map›Paper›PMID 19774113›Full record

ArticleInternational journal of nanomedicine2009

The use of superparamagnetic nanoparticles for prosthetic biofilm prevention.

Erik N Taylor, Thomas J Webster

Abstract read
In one paragraph

Article in International journal of nanomedicine, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed.

  1. Review
  2. Iron Oxide-Based Magnetic Nanoparticles in Oral Infection Control.International journal of nanomedicine · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Selected strategies to fight pathogenic bacteria.Journal of enzyme inhibition and medicinal chemistry · 2023
    Review
  8. Article
  9. Article
  10. Review
  11. Hope for bone regeneration: The versatility of iron oxide nanoparticles.Frontiers in bioengineering and biotechnology · 2022
    Review
  12. Article
  13. Review
  14. Influence of CeInternational journal of molecular sciences · 2021
    Article
  15. Review
  16. Review
  17. Review
  18. Article
  19. Article
  20. Biofilm inhibition, modulation of virulence and motility properties by FeOOH nanoparticle in Pseudomonas aeruginosa.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Erik N TaylorNanomedicine Laboratories, Division of Engineering, and Department of Orthopaedics, Brown University, Providence, RI 02912, USA.
Thomas J Webster

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As with all surgical procedures, implantation comes with the added risk of infection. The goal of this in vitro study was to explore the use of superparamagnetic iron oxide nanoparticles (SPION) as a multifunctional platform to prevent biofilm formation. Results showed for the first time decreased Staphylococcus epidermidis numbers when exposed to 100 microg/ml of SPION for 12 hours and this trend continued for up to 48 hours. Prevention of colony assembly, a prerequisite to biofilm formation, was also observed at lower SPION dosages of 10 microg/ml after 12 hours. Coupled with previous studies demonstrating enhanced bone cell functions in the presence of the same concentration of SPION, the present results provided much promise for the use of SPION for numerous anti-infection orthopedic applications.

Indexed as

Anti-Bacterial AgentsApoptosisBiofilmsCell ProliferationFerric CompoundsHumansMagneticsNanoparticlesProsthesis-Related InfectionsStaphylococcal InfectionsStaphylococcus epidermidisAnti-Bacterial AgentsFerric Compoundsferric oxidebiofilmnanomedicinenanotechnologyprosthetic infectionStaphylococcus epidermidissuperparamagnetic iron oxide nanoparticles (SPION)

Identifiers

PMID19774113
PMCPMC2747349

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.