Evidence map›Paper›PMID 19770649›Full record

ReviewCurrent opinion in endocrinology, diabetes, and obesity2009

Disorders of the growth plate.

Chanika Phornphutkul, Philip A Gruppuso

Abstract readReview
In one paragraph

Review in Current opinion in endocrinology, diabetes, and obesity, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Primary cilia support cartilage regeneration after injury.International journal of oral science · 2023
    Article
  2. Review
  3. Article
  4. Review
  5. The Role ofJBMR plus · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Chanika PhornphutkulDepartment of Pediatrics, Rhode Island Hospital, Warren Alpert Medical School of Brown University, Providence, Rhode Island 02903, USA. Chanika_Phornphutkul@brown.edu
Philip A Gruppuso

Funding

RI COBRE: REGULATION OF GROWTH PLATE DEVELOPMENT BYNUCLEAR/CYTOPLASMIC FACTORSP20RR024484 · NCRR · RHODE ISLAND HOSPITAL · PI BOSTOM, ANDREW G. · 2007 to 2011
$11.9M
NCRR NIH HHS P20 RR024484
6 · The paper itself

Abstract

purpose of reviewTo summarize the recent advances in our understanding of the majors genes involved in chondrogenesis and their molecular mechanisms. RECENT

findingsDisorders of the growth plate and the resulting skeletal dysplasias are a consequence of defects in genes involved in various stages of the chondrocyte proliferation and differentiation process. Recent identification of disease genes has provided insights into the pathophysiology of many skeletal dysplasias. SUMMARY: This knowledge enhances our understanding of the physiology and pathophysiology of the growth plate. Many skeletal dysplasias can now be characterized at the molecular level, allowing clinicians to provide accurate molecular diagnoses and counseling. Further research in this area will likely provide insights into possible therapeutic options for disorders of the growth plate.

Indexed as

Bone DevelopmentAnimalsBone Diseases, DevelopmentalChondrogenesisGrowth DisordersGrowth PlateHumans

Identifiers

PMID19770649
PMCPMC2894809

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.