ArticleThe Journal of physiology2009
Frequency-dependent disynaptic inhibition in the pyramidal network: a ubiquitous pathway in the developing rat neocortex.
Article in The Journal of physiology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
57 citing papers in PubMed, 93 citations in OpenAlex.
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- Pharmacological Signature and Target Specificity of Inhibitory Circuits Formed by Martinotti Cells in the Mouse Barrel Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Transcranial Magnetic Stimulation and Neocortical Neurons: The Micro-Macro Connection.Frontiers in neuroscience · 2022Review
- Dynamics of a Mutual Inhibition Circuit between Pyramidal Neurons Compared to Human Perceptual Competition.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
- Contextual Integration in Cortical and Convolutional Neural Networks.Frontiers in computational neuroscience · 2020Article
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- Complementary networks of cortical somatostatin interneurons enforce layer specific control.eLife · 2019Article
- Lateral inhibition by Martinotti interneurons is facilitated by cholinergic inputs in human and mouse neocortex.Nature communications · 2018Article
- Slot-like capacity and resource-like coding in a neural model of multiple-item working memory.Journal of neurophysiology · 2018Article
- Specialized Subpopulations of Deep-Layer Pyramidal Neurons in the Neocortex: Bridging Cellular Properties to Functional Consequences.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2018Review
- Two types of somatostatin-expressing GABAergic interneurons in the superficial layers of the mouse cingulate cortex.PloS one · 2018Article
- Long-latency suppression of auditory and somatosensory change-related cortical responses.PloS one · 2018Article
- Activity dependent feedback inhibition may maintain head direction signals in mouse presubiculum.Nature communications · 2017Article
- Chrna2-Martinotti Cells Synchronize Layer 5 Type A Pyramidal Cells via Rebound Excitation.PLoS biology · 2017Article
- Distinct Activity Profiles of Somatostatin-Expressing Interneurons in the Neocortex.Frontiers in cellular neuroscience · 2017Article
- A Detailed Data-Driven Network Model of Prefrontal Cortex Reproduces Key Features of In Vivo Activity.PLoS computational biology · 2016Article
- GABAergic interneurons form transient layer-specific circuits in early postnatal neocortex.Nature communications · 2016Article
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The general structure of the mammalian neocortex is remarkably similar across different cortical areas. Despite certain cytoarchitectural specializations and deviations from the general blueprint, the principal organization of the neocortex is relatively uniform. It is not known, however, to what extent stereotypic synaptic pathways resemble each other between cortical areas, and how far they might reflect possible functional uniformity or specialization. Here, we show that frequency-dependent disynaptic inhibition (FDDI) is a generic circuit motif that is present in all neocortical areas we investigated (primary somatosensory, auditory and motor cortex, secondary visual cortex and medial prefrontal cortex of the developing rat). We did find, however, area-specific differences in occurrence and kinetics of FDDI and the short-term dynamics of monosynaptic connections between pyramidal cells (PCs). Connectivity between PCs, both monosynaptic and via FDDI, is higher in primary cortices. The long-term effectiveness of FDDI is likely to be limited by an activity-dependent attenuation of the PC-interneuron synaptic transmission. Our results suggest that the basic construction of neocortical synaptic pathways follows principles that are independent of modality or hierarchical order within the neocortex.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.