Evidence map›Paper›PMID 19770178›Full record

ReviewThe Journal of endocrinology2010

Current views on type 2 diabetes.

Yi Lin, Zhongjie Sun

Open access · bronzeAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in The Journal of endocrinology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 147 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
147citing papers in PubMed, 6 pooled it
10.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

147 citing papers in PubMed, 6 syntheses or guidelines pooled it, 462 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Systematic review and meta-analysis ofFrontiers in pharmacology · 2022
    Pooled it
  4. Pooled it
  5. TheJournal of diabetes research · 2016
    Pooled it
  6. Pooled it
  7. Trial
  8. Review
  9. Article
  10. Article
  11. Review
  12. Therapeutic potential ofFrontiers in nutrition · 2025
    Review
  13. Review
  14. Incretin-based therapy: a new horizon in diabetes management.Journal of diabetes and metabolic disorders · 2024
    Review
  15. Article
  16. Review
  17. Review
  18. Article
  19. Vitamin BIrish journal of medical science · 2024
    Review
  20. Article

87 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Yi LinDepartment of Physiology, College of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma 73104, USA.
Zhongjie Sun
University of Oklahoma · USUniversity of Oklahoma Health Sciences Center · US

Funding

Intermittent Cold Exposure on the Endothelin SystemR01HL077490 · NHLBI · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI SUN, ZHONGJIE · 2006 to 2010
$1.8M
NHLBI NIH HHS HL077490NHLBI NIH HHS R01 HL077490
6 · The paper itself

Abstract

Type 2 diabetes mellitus (T2DM) affects a large population worldwide. T2DM is a complex heterogeneous group of metabolic disorders including hyperglycemia and impaired insulin action and/or insulin secretion. T2DM causes dysfunctions in multiple organs or tissues. Current theories of T2DM include a defect in insulin-mediated glucose uptake in muscle, a dysfunction of the pancreatic beta-cells, a disruption of secretory function of adipocytes, and an impaired insulin action in liver. The etiology of human T2DM is multifactorial, with genetic background and physical inactivity as two critical components. The pathogenesis of T2DM is not fully understood. Animal models of T2DM have been proved to be useful to study the pathogenesis of, and to find a new therapy for, the disease. Although different animal models share similar characteristics, each mimics a specific aspect of genetic, endocrine, metabolic, and morphologic changes that occur in human T2DM. The purpose of this review is to provide the recent progress and current theories in T2DM and to summarize animal models for studying the pathogenesis of the disease.

Indexed as

AdipocytesAnimalsBiological TransportDiabetes Mellitus, Type 2Disease Models, AnimalEndocrinologyGlucoseHumansInsulinInsulin-Secreting CellsLiverSignal TransductionGlucoseInsulin

Identifiers

PMID19770178
PMCPMC2814170
OpenAlexW2135326009

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.