Evidence map›Paper›PMID 19769004›Full record

ArticleEthnicity & disease2009

Race/ethnic and sex differences in large and small artery elasticity--results of the multi-ethnic study of atherosclerosis (MESA).

Daniel A Duprez, David R Jacobs, Pamela L Lutsey, David Herrington, Darryl Prime, Pamela Ouyang, R Graham Barr, David A Bluemke

Abstract read
In one paragraph

Article in Ethnicity & disease, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 1 synthesis or guideline pooled it, 57 citations in OpenAlex.

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  20. The effects of age on pulse wave velocity in untreated hypertension.Journal of clinical hypertension (Greenwich, Conn.) · 2018
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Daniel A DuprezCardiovascular Division, Medical School University of Minnesota, Minneapolis, MN 55455, USA. dupre007@umn.edu
David R Jacobs
Pamela L Lutsey
David Herrington
Darryl Prime
Pamela Ouyang
R Graham Barr
David A Bluemke
Johns Hopkins University · USUniversity of Minnesota · USWake Forest University · USColumbia University · USUniversity of Minnesota Medical Center · US

Funding

Molecular Biomedical Imaging Laboratory (NIBIB)ZIAEB000072 · NIBIB · NATIONAL INSTITUTE OF BIOMEDICAL IMAGING AND BIOENGINEERING · PI BLUEMKE, DAVID · 2010 to 2017
$5.0M
Establishment of Molecular Biomedical Imaging LaboratoryZIAEB000065 · NIBIB · NATIONAL INSTITUTE OF BIOMEDICAL IMAGING AND BIOENGINEERING · PI BLUEMKE, DAVID · 2009 to 2009
$1.0M
SUBCLINICAL CARDIOVASCULAR DISEASE STUDY--FIELD CENTERN01HC095163 · HC · UNIVERSITY OF MINNESOTA TWIN CITIES · PI FOLSOM, AARON R · 1999 to 2001
$443k
Molecular Biomedical Imaging Laboratory (CC)ZIACL090019 · CLC · CLINICAL CENTER · PI JONES, ELIZABETH C. · 2010 to 2017
$0k
Intramural NIH HHS Z99 CL999999Intramural NIH HHS ZIA CL090019Intramural NIH HHS ZIA EB000072NHLBI NIH HHS N01 HC095163
6 · The paper itself

Abstract

objectiveReduction in arterial elasticity marks progression toward cardiovascular morbidity and mortality. Variability in arterial elasticity may help account for race/ethnic and gender differences in cardiovascular risk.

designCross-sectional study.

settingWhites, African Americans, Hispanics and Chinese aged 45-84 years free of clinically recognized cardiovascular disease were recruited in six US communities.

participantsWe examined 3,316 women and 3,020 men according to race/ethnicity and sex.

main outcome measuresLarge (LAE) and small artery (SAE) elasticity, derived from radial artery diastolic pulse wave contour registration in all subjects in a supine position using tonometry. LAE and SAE were adjusted for ethnicity, age, clinical site, height, heart rate, blood pressure, antihypertensive medication and body mass index, diabetes, smoking, and circulating lipids.

resultsMuch of the sex difference in arterial elasticity was explained by height. After adjustment, LAE did not differ by race/ ethnicity, but mean SAE in African Americans was 4.2 mL/mm Hg x 100 and 4.4 mL/ mm Hg x 100 in Hispanics compared to means of 4.6 mL/mm Hg x 100 in Whites, and 4.8 mL/mm Hg x 100 in Chinese.

conclusionsReduced SAE may indicate earlier vascular disease in African Americans and Hispanics than other groups.

Indexed as

ElasticityAgedAged, 80 and overArteriesAsian PeopleAtherosclerosisBlack or African AmericanBody HeightCross-Sectional StudiesFemaleHispanic or LatinoHumansMaleManometryMiddle AgedSex Factors

Identifiers

PMID19769004
PMCPMC2924814
OpenAlexW1554972960

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.