ArticleNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2009
Neurosyphilis in the age of AIDS: clinical and laboratory features.
Article in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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7 citing papers in PubMed.
- Symptomatic neurosyphilis in HIV-negative patients: a retrospective cohort study.Frontiers in public health · 2025Article
- Analysis of Fourteen New Cases of Meningovascular Syphilis: Renewed Interest in an Old Problem.Cureus · 2021Article
- The clinical and laboratory features of neurosyphilis in HIV-infected patients: A retrospective study in 92 patients.Medicine · 2018Observational
- How Well Do Neurologic Symptoms Identify Individuals With Neurosyphilis?Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2018Article
- Clinical and laboratory characteristics of ocular syphilis: a new face in the era of HIV co-infection.Journal of ophthalmic inflammation and infection · 2015Article
- Observational
- Neurological Findings in Early Syphilis: a Comparison Between HIV Positive and Negative Patients.Neurology international · 2013Article
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Abstract
Neurosyphilis remains to be a challenging diagnostic possibility worldwide. The aim of our study was to identify and report the clinical and laboratory profile of neurosyphilis, comparing features of HIV-infected and HIV-negative patients. A retrospective investigation of all cases of neurosyphilis, defined as positive VDRL test on cerebrospinal fluid, diagnosed at Hospital das Clínicas, Ribeirão Preto School of Medicine between January 1988 and December 2005, was carried out. We identified 35 patients with a mean age of 42.1 years, 28.6% of them HIV infected and 74.3% of them were male. HIV-infected patients were younger (34.6 years), presented with a higher frequency of the early forms of neurosyphilis, higher titers of serum VDRL and higher mean proteinorrachia at the suboccipital level. Neurosyphilis is still characterized by clinical polymorphism and there are significant differences in its epidemiological, clinical and laboratory profile when HIV-infected patients are compared with HIV-negative patients.
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