Evidence map›Paper›PMID 19768134›Full record

ReviewInfluenza and other respiratory viruses2009

Diversity of influenza viruses in swine and the emergence of a novel human pandemic influenza A (H1N1).

Christy Brockwell-Staats, Robert G Webster, Richard J Webby

Open access · greenAbstract readReview
In one paragraph

Review in Influenza and other respiratory viruses, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 84 papers.

0numbers the graph read from it
0cells of the map it votes in
84citing papers in PubMed
10.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

84 citing papers in PubMed, 157 citations in OpenAlex.

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  7. Promising Vaccine Formulations for Emerging Infectious Diseases.International journal of molecular sciences · 2025
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24 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Christy Brockwell-StaatsDivision of Virology, Department of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
Robert G Webster
Richard J Webby
St. Jude Children's Research Hospital · USUniversity of Tennessee Health Science Center · US

Funding

NIAID NIH HHS HHSN266200700005C
6 · The paper itself

Abstract

The novel H1N1 influenza virus that emerged in humans in Mexico in early 2009 and transmitted efficiently in the human population with global spread has been declared a pandemic strain. Here we review influenza infections in swine since 1918 and the introduction of different avian and human influenza virus genes into swine influenza viruses of North America and Eurasia. These introductions often result in viruses of increased fitness for pigs that occasionally transmit to humans. The novel virus affecting humans is derived from a North American swine influenza virus that has acquired two gene segments [Neuraminidase (NA) and Matrix (M)] from the European swine lineages. This reassortant appears to have increased fitness in humans. The potential for increased virulence in humans and of further reassortment between the novel H1N1 influenza virus and oseltamivir resistant seasonal H1N1 or with highly pathogenic H5N1 influenza stresses the need for urgent pandemic planning.

Indexed as

Genetic VariationPandemicsAnimalsAsiaDisease OutbreaksEuropeHumansInfluenza A Virus, H1N1 SubtypeInfluenza, HumanNorth AmericaOrthomyxoviridae InfectionsSwineSwine DiseasesZoonoses

Identifiers

PMID19768134
PMCPMC2746644
OpenAlexW2147901189

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.