Trial reportJournal of dental research2009
Mechanical properties of tannic-acid-treated dentin matrix.
Trial report in Journal of dental research, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
54 citing papers in PubMed, 3 syntheses or guidelines pooled it, 128 citations in OpenAlex.
- Effect of mussel-inspired primers on resin-dentin bonding interface stability: A systematic review and meta-analysis.European journal of oral sciences · 2025Pooled it
- Pooled it
- Mechanisms regulating the degradation of dentin matrices by endogenous dentin proteases and their role in dental adhesion. A review.American journal of dentistry · 2014Pooled it
- Effects of phytic and tannic acids on dentin bonding, nanoleakage, and micropermeability under wet and dry bonding techniques.Odontology · 2026Article
- Effects of phytic and tannic acids on dentin bonding, nanoleakage, and micropermeability under wet and dry bonding techniques.Odontology · 2026Article
- The contribution of different types of polyphenols to bonding performance by enhancing the stabilization of the hybrid layer.Clinical oral investigations · 2026Article
- Development of molecularly imprinted vegetarian membranes (MIP-VMs) for oral tissue repair and regeneration.Frontiers in bioengineering and biotechnology · 2026Article
- Advances in Bioactive Dental Adhesives for Caries Prevention: A State-of-the-Art Review.Journal of functional biomaterials · 2025Review
- Impact of collagen cross-linking agents on release of hydroxyproline from radicular dentin in endodontically treated mandibular premolars with bio-ceramic sealers: AnJournal of conservative dentistry and endodontics · 2025Article
- Biomineralization of dental tissues with natural drugs: a comprehensive review.The Saudi dental journal · 2025Review
- A dual action approach of B-type proanthocyanidins for silencing enzymatic activity and sealing natural caries-affected dentin-resin interfaces.Journal of dentistry · 2025Article
- Unleashing the Potential of Tannic Acid in Dentistry: A Scoping Review of Applications.Bioengineering (Basel, Switzerland) · 2025Review
- Exosome-loaded tannic acid-thioctic acid hydrogel enhances wound healing in coagulation disorders.Materials today. Bio · 2025Article
- Investigating the Effect of Staining Beverages on the Structural and Mechanical Integrity of Dental Composites Using Raman, Fourier Transform Infrared (FTIR) Spectroscopy, and Microhardness Analysis.Medicina (Kaunas, Lithuania) · 2025Article
- Natural Strategies for Dental Hard-Tissue Remineralization: A Scoping Review of Galla Chinensis and Its Dual Anticaries Action.Clinical, cosmetic and investigational dentistry · 2025Review
- Effect of natural antioxidants on bond strength recovery of resin-modified glass ionomers to the NaOCl-affected pulp chamber dentin.Clinical and experimental dental research · 2023Article
- Molecular interactions of tannic acid and matrix metalloproteinases 2 and 9.Computational and structural biotechnology journal · 2023Article
- Condensed tannins act as anthelmintics by increasing the rigidity of the nematode cuticle.Scientific reports · 2022Article
- Galloylated proanthocyanidins in dentin matrix exhibit biocompatibility and induce differentiation in dental stem cells.Journal of bioactive and compatible polymers · 2022Article
- Tannic acid induces dentin biomineralization by crosslinking and surface modification.RSC advances · 2022Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
Dentin collagen is a major component of the hybrid layer, and its stability may have a great impact on the properties of adhesive interfaces. We tested the hypothesis that the use of tannic acid (TA), a collagen cross-linking agent, may affect the mechanical properties and stability of the dentin matrix. The present study evaluated the effects of different concentrations of TA on the modulus of elasticity and enzymatic degradation of dentin matrix. Hence, the effect of TA pre-treatment on resin-dentin bond strength was assessed with the use of two bonding systems. Sound human molars were used and prepared according to each experimental design. The use of TA affected the properties of demineralized dentin by increasing its stiffness. TA treatment inhibited the effect of collagenase digestion on dentin matrix, particularly for 10%TA and 20%TA. The TA-dentin matrix complex resulted in improved bond strength for both adhesive systems.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.