ArticleThe Journal of experimental medicine1990
Human immunodeficiency virus type 1-infected individuals make autoantibodies that bind to CD43 on normal thymic lymphocytes.
Article in The Journal of experimental medicine, 1990. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 67 citations in OpenAlex.
- Breaking the Glyco-Code of HIV Persistence and Immunopathogenesis.Current HIV/AIDS reports · 2019Review
- Human Galectin-9 Is a Potent Mediator of HIV Transcription and Reactivation.PLoS pathogens · 2016Article
- Reduced CD43 expression on the neutrophils of MDS patients correlates with an activated phenotype of these cells.International journal of hematology · 2001Article
- Phagocytosis stimulates alternative glycosylation of macrosialin (mouse CD68), a macrophage-specific endosomal protein.The Biochemical journal · 1999Article
- CD43, a molecule with multiple functions.Immunologic research · 1999Review
- Branched O-linked oligosaccharides ectopically expressed in transgenic mice reduce primary T-cell immune responses.The EMBO journal · 1997Article
- Cross-linking of Fas by antibodies to a peculiar domain of gp120 V3 loop can enhance T cell apoptosis in HIV-1-infected patients.The Journal of experimental medicine · 1996Article
- Polymorphic epithelial mucin (MUC-1)-containing circulating immune complexes in carcinoma patients.British journal of cancer · 1995Article
- Expression of the T antigen on a T-lymphoid cell line, supT1.Glycoconjugate journal · 1995Article
- HIV-mediated B-lymphocyte activation and lymphomagenesis.Journal of clinical immunology · 1995Review
- Disregulation of leukosialin (CD43, Ly48, sialophorin) expression in the B-cell lineage of transgenic mice increases splenic B-cell number and survival.Proceedings of the National Academy of Sciences of the United States of America · 1995Article
- Altered glycosylation of leukosialin, CD43, in HIV-1-infected cells of the CEM line.The Journal of experimental medicine · 1994Article
- Anti-lymphocyte antibodies in plasma of HIV-1-infected patients preferentially react with MHC class II-negative T cells and are linked to antibodies against gp41.Clinical and experimental immunology · 1994Article
- Albumin inhibits neutrophil spreading and hydrogen peroxide release by blocking the shedding of CD43 (sialophorin, leukosialin).The Journal of cell biology · 1993Article
- Article
- Pathogenesis of human immunodeficiency virus infection.Microbiological reviews · 1993Review
- Differential epitope expression of Ly-48 (mouse leukosialin).Immunogenetics · 1993Article
- CD43 interferes with T-lymphocyte adhesion.Proceedings of the National Academy of Sciences of the United States of America · 1992Article
- Differential isotype expression and binding properties of T cell-reactive antibodies in human immunodeficiency virus (HIV) infection.Journal of clinical immunology · 1992Article
- Amino acid sequence of human plasma galactoglycoprotein: identity with the extracellular region of CD43 (sialophorin).Proceedings of the National Academy of Sciences of the United States of America · 1992Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Sera from human immunodeficiency virus type 1 (HIV-1)-infected and -noninfected individuals were screened for antibodies that could bind to native T cell differentiation antigens. Antibodies that could immunoprecipitate CD43 (sialophorin, leukosialin) from a T cell lymphoma line were detected in sera from 27% of patients, and antibodies that could bind specifically to transfected cells expressing CD43 were detected in 47% of patients. The anti-CD43 antibodies were related to HIV-1 infection in that no patients with other chronic viral infections or systemic lupus erythematosus contained such antibodies in their sera. The anti-CD43 autoantibodies bound to a partially sialylated form of CD43 expressed by normal human thymocytes, but not by normal, circulating T lymphocytes. However, the determinant(s) recognized by the anti-CD43 autoantibodies was present on a large proportion of circulating T lymphocytes, but masked from antibody recognition by sialic acid residues. These results demonstrate that HIV-1 infection is specifically associated with the production of autoantibodies that bind to a native T cell surface antigen.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.