Evidence map›Paper›PMID 19766635›Full record

ReviewFEBS letters2009

System-level design of bacterial cell cycle control.

Harley H McAdams, Lucy Shapiro

Open access · bronzeAbstract readReview
In one paragraph

Review in FEBS letters, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 52 citations in OpenAlex.

  1. Article
  2. A novel mode of histone-like protein HupB regulatingCurrent research in microbial sciences · 2025
    Review
  3. Review
  4. Review
  5. Article
  6. Chemical synthesis rewriting of a bacterial genome to achieve design flexibility and biological functionality.Proceedings of the National Academy of Sciences of the United States of America · 2019
    Article
  7. Article
  8. Article
  9. Dynamic translation regulation in Caulobacter cell cycle control.Proceedings of the National Academy of Sciences of the United States of America · 2016
    Article
  10. Cell cycle progression in Caulobacter requires a nucleoid-associated protein with high AT sequence recognition.Proceedings of the National Academy of Sciences of the United States of America · 2016
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Harley H McAdamsDepartment of Developmental Biology, Stanford University School of Medicine, Stanford, CA 94305, USA. hmcadams@stanford.edu
Lucy Shapiro
Stanford University · US

Funding

REGULATION OF DIFFERENTIATION IN CAULOBACTERR01GM032506 · NIGMS · YESHIVA UNIVERSITY · PI SHAPIRO, LUCILLE · 1985 to 2014
$7.1M
3D Chromosome/Replisome Positioning in Bacterial CellsR24GM073011 · NIGMS · STANFORD UNIVERSITY · PI SHAPIRO, LUCILLE · 2005 to 2008
$1.5M
REGULATION OF DIFFERENTIATION IN CAULOBACTERR37GM032506 · NIGMS · STANFORD UNIVERSITY · PI SHAPIRO, LUCILLE · 1993 to 2002
$1.4M
NIGMS NIH HHS GM073001NIGMS NIH HHS GM32506NIGMS NIH HHS GM51426NIGMS NIH HHS R24 GM073011
6 · The paper itself

Abstract

Understanding of the cell cycle control logic in Caulobacter has progressed to the point where we now have an integrated view of the operation of an entire bacterial cell cycle system functioning as a state machine. Oscillating levels of a few temporally-controlled master regulator proteins in a cyclical circuit drive cell cycle progression. To a striking degree, the cell cycle regulation is a whole cell phenomenon. Phospho-signaling proteins and proteases dynamically deployed to specific locations on the cell wall are vital. An essential phospho-signaling system integral to the cell cycle circuitry is central to accomplishing asymmetric cell division.

Indexed as

Cell CycleBacterial ProteinsCaulobacter crescentusCell DivisionDNA-Binding ProteinsDNA MethylationGene Expression Regulation, BacterialPhosphoproteinsSignal TransductionTranscription FactorsBacterial ProteinsCtrA protein, CaulobacterDNA-Binding ProteinsPhosphoproteinsTranscription Factors

Identifiers

PMID19766635
PMCPMC2795017
OpenAlexW2074791937

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.