ReviewTrends in microbiology2009
Bacteriophages as model organisms for virus emergence research.
Review in Trends in microbiology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 41 citations in OpenAlex.
- Nicking Activity of M13 Bacteriophage Protein 2.International journal of molecular sciences · 2025Article
- Article
- Coevolution between marine Aeromonas and phages reveals temporal trade-off patterns of phage resistance and host population fitness.The ISME journal · 2023Article
- Host-Dependent Differences in Replication Strategy of theFrontiers in microbiology · 2020Article
- Evolutionary ecology of virus emergence.Annals of the New York Academy of Sciences · 2017Review
- The coupon collector urn model with unequal probabilities in ecology and evolution.Journal of the Royal Society, Interface · 2017Review
- Evolutionary interpretations of mycobacteriophage biodiversity and host-range through the analysis of codon usage bias.Microbial genomics · 2016Article
- Poly-γ-Glutamic Acid: Biodegradable Polymer for Potential Protection of Beneficial Viruses.Materials (Basel, Switzerland) · 2016Article
- Genomic and Gene-Expression Comparisons among Phage-Resistant Type-IV Pilus Mutants of Pseudomonas syringae pathovar phaseolicola.PloS one · 2015Article
- Article
- Experimental selection reveals a trade-off between fecundity and lifespan in the coliphage Qß.Open biology · 2013Article
- What limits the evolutionary emergence of pathogens?Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2013Article
- Understanding specialism when the Jack of all trades can be the master of all.Proceedings. Biological sciences · 2012Review
- Evolutionary genomics of host-use in bifurcating demes of RNA virus phi-6.BMC evolutionary biology · 2012Article
- Repeatability and contingency in the evolution of a key innovation in phage lambda.Science (New York, N.Y.) · 2012Article
- What Can Phages Tell Us about Host-Pathogen Coevolution?International journal of evolutionary biology · 2012Article
- Experimental evidence that source genetic variation drives pathogen emergence.Proceedings. Biological sciences · 2010Article
- Risk factors for the evolutionary emergence of pathogens.Journal of the Royal Society, Interface · 2010Article
- Combining mathematics and empirical data to predict emergence of RNA viruses that differ in reservoir use.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2010Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Viruses fully emerge by gaining the ability to sustainably infect new host populations. When the hosts are humans, emerging viruses can present major public health issues, as exemplified by the AIDS pandemic. Therefore, heuristic approaches to identify nascent diseases before they become pandemic would be valuable. Unfortunately, the current patient-based and epidemiological approaches are ill-suited in this regard because they are largely responsive and not predictive. Alternative approaches based on virus evolutionary ecology might have greater potential to predict virus emergence. However, given the difficulties encountered when studying metazoan viruses in this context, the development of new model systems is greatly desirable. Here, I highlight studies that show that bacteriophages are appropriate model organisms for virus emergence research because of the ease in which important population parameters can be manipulated. Ideally this research will permit identifying major factors determining the persistence or extinction of emerging viruses. If such viruses could be recognized in advance, patient-based and epidemiological strategies could be better mobilized to deal with them.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.