Evidence map›Paper›PMID 19765542›Full record

ArticleActa tropica2010

Schistosoma mansoni infection in a rural area of the Jequitinhonha Valley, Minas Gerais, Brazil: analysis of exposure risk.

Wesley Rodrigues Pereira, Helmut Kloos, Sara B Crawford, Jorge Gustavo Velásquez-Melendez, Leonardo Ferreira Matoso, Ricardo Toshio Fujiwara, Guilherme Grossi Lopes Cançado, Philip T Loverde, Rodrigo Correa-Oliveira, Andrea Gazzinelli

Abstract read
In one paragraph

Article in Acta tropica, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Wesley Rodrigues PereiraLaboratory of Cellular and Molecular Immunology, Centro de Pesquisas René Rachou/FIOCRUZ, Brazil.
Helmut Kloos
Sara B Crawford
Jorge Gustavo Velásquez-Melendez
Leonardo Ferreira Matoso
Ricardo Toshio Fujiwara
Guilherme Grossi Lopes Cançado
Philip T Loverde
Rodrigo Correa-Oliveira
Andrea Gazzinelli
Fundação Oswaldo Cruz · BRUniversidade Federal de Minas Gerais · BRThe University of Texas Health Science Center at San Antonio · USUniversity of California, San Francisco · USValparaiso University · US

Funding

Training to Enhance Schistosomiasis Research in BrazilD43TW006580 · FIC · TEXAS BIOMEDICAL RESEARCH INSTITUTE · PI LOVERDE, PHILIP T · 2003 to 2007
$726k
Spatial clustering pre and post-treatment for schistosomiasis and geohelminthsR03AI071057 · NIAID · UNIVERSIDADE FEDERAL DE MINAS GERAIS · PI GAZZINELLI, ANDREA · 2008 to 2009
$130k
FIC NIH HHS 1D43TW006580FIC NIH HHS D43 TW006580NIAID NIH HHS 1R03AI071057-01NIAID NIH HHS R03 AI071057PHS HHS A145451
6 · The paper itself

Abstract

This study examines the relative contribution of age-specific total IgE levels, eosinophils and water contact behavior to the prevalence and intensity (geometric mean egg counts) of Schistosoma mansoni infection in the poor rural population of Virgem das Graças in northern Minas Gerais State. In bivariate analysis, age was strongly correlated with both prevalence and intensity of infection, while eosinophil levels with prevalence only (p<0.0001); IgE levels and 5 demographic and socioeconomic variables were moderately correlated with prevalence (p<0.05), as were number of persons per room and TBM (total body minutes) with egg counts. In multivariate analysis, after controlling for demographic and socioeconomic factors, only total IgE levels were significantly correlated with both prevalence (p=0.248, 95% CI=1.01-1.11) and intensity (p=0.0217, 95% CI=0.01-0.14) of infection and eosinophil levels with prevalence (p=0.0005, 95% CI=1.07-1.24). Although any causal relationship cannot be confirmed by a cross-sectional study, we demonstrated an associated decrease in prevalence and intensity of S. mansoni infection with increased IgE levels.

Indexed as

AdolescentAdultAnimalsAntibodies, HelminthAntibody SpecificityBrazilChildEnvironmental ExposureEosinophilsFemaleHumansImmunoglobulin ELeukocyte CountMaleMiddle AgedParasite Egg CountAntibodies, HelminthImmunoglobulin EWater

Identifiers

PMID19765542
PMCPMC2784266
OpenAlexW1989306877

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.