ReviewImmunologic research2010
Review: Is lung inflammation associated with microbes and microbial toxins in cigarette tobacco smoke?
Review in Immunologic research, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 24 citations in OpenAlex.
- Mentholation triggers brand-specific shifts in the bacterial microbiota of commercial cigarette products.Applied microbiology and biotechnology · 2020Article
- Perspective: The Lung, Particles, Fibers, Nanomaterials, and Autoimmunity.Frontiers in immunology · 2020Review
- Little cigars and cigarillos harbor diverse bacterial communities that differ between the tobacco and the wrapper.PloS one · 2019Article
- The Contribution of Small Airway Obstruction to the Pathogenesis of Chronic Obstructive Pulmonary Disease.Physiological reviews · 2017Review
- Lung inflammation caused by inhaled toxicants: a review.International journal of chronic obstructive pulmonary disease · 2016Review
- Exacerbation of Chronic Obstructive Pulmonary Disease.Cell biochemistry and biophysics · 2015Review
- High Seroprevalence of Bordetella pertussis in Patients with Chronic Obstructive Pulmonary Disease: A Case-Control Study.Tanaffos · 2015Article
- Optical detection of preneoplastic lesions of the central airways.ISRN oncology · 2012Article
- TLR4 protein contributes to cigarette smoke-induced matrix metalloproteinase-1 (MMP-1) expression in chronic obstructive pulmonary disease.The Journal of biological chemistry · 2011Article
- Induction of the unfolded protein response by cigarette smoke is primarily an activating transcription factor 4-C/EBP homologous protein mediated process.International journal of chronic obstructive pulmonary disease · 2011Article
- Cigarette filter-based assays as proxies for toxicant exposure and smoking behavior--a literature review.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2009Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chronic inflammation that has been observed for malignant and non-neoplastic lung diseases of smokers has been attributed to the numerous and diverse particulate ('tar')-phase and gas-phase chemicals in mainstream smoke, most of which arise from the burning of tobacco. The primary cell-mediator of lung inflammation is the macrophage. Most probably, inflammation is promoted also from some of the more than 50 other cell types of the lung. Cured tobacco in diverse types of cigarettes is known to harbor a plethora of bacteria (Gram-positive and Gram-negative), fungi (mold, yeast), spores, and is rich in endotoxin (lipopolysaccharide). Reviewed herein are recent observations of the authors' team and other investigators that support the hypothesis that lung inflammation of long-term smokers may be attributed in part to tobacco-associated bacterial and fungal components that have been identified in tobacco and tobacco smoke.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.