ReviewJapanese journal of ophthalmology2009
Intrinsic optical signal imaging of retinal activation.
Review in Japanese journal of ophthalmology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 14 citations in OpenAlex.
- Functional Optical Coherence Tomography for Intrinsic Signal Optoretinography: Recent Developments and Deployment Challenges.Frontiers in medicine · 2022Review
- Detection of cellular micromotion by advanced signal processing.Scientific reports · 2020Article
- Fast intrinsic optical signal correlates with activation phase of phototransduction in retinal photoreceptors.Experimental biology and medicine (Maywood, N.J.) · 2020Review
- In vivo super-resolution imaging of transient retinal phototropism evoked by oblique light stimulation.Journal of biomedical optics · 2018Article
- In vivo optical coherence tomography of stimulus-evoked intrinsic optical signals in mouse retinas.Journal of biomedical optics · 2016Article
- Article
- Intrinsic optical signal imaging of retinal physiology: a review.Journal of biomedical optics · 2015Review
- Impact of motion-associated noise on intrinsic optical signal imaging in humans with optical coherence tomography.Biomedical optics express · 2015Article
- Super-Resolution Scanning Laser Microscopy Based on Virtually Structured Detection.Critical reviews in biomedical engineering · 2015Review
- Functional imaging of retinal photoreceptors and inner neurons using stimulus-evoked intrinsic optical signals.Methods in molecular biology (Clifton, N.J.) · 2012Article
- In vivo confocal imaging of fast intrinsic optical signals correlated with frog retinal activation.Optics letters · 2011Article
- High-speed line-scan confocal imaging of stimulus-evoked intrinsic optical signals in the retina.Optics letters · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fast intrinsic optical signals (IOSs) correlated with stimulus-activated retinal responses are reviewed. Fast IOSs have a time course comparable to the stimulus-evoked electrophysiological kinetics of the retina, and thus promise a new methodology for high-resolution evaluation of the physiological health of the retina. However, practical application of fast IOSs for retinal study and diagnosis is challenging because of their low sensitivity and limited specificity. Using isolated amphibian retinas, a series of experiments to optimize and characterize fast IOSs has been conducted. Fast, high-resolution nearinfrared light imaging disclosed both positive (increasing) and negative (decreasing) optical responses in adjacent retinal areas, which satisfied spatial resolution essential to the differentiation of IOSs from opposite polarities. At the subcellular (approximately microm) level, fast IOSs often exceeded 5% DeltaI/I, where I is the dynamic optical change, and I is the background light intensity. Experiments with isolated frog retinas suggest that negative IOSs stem primarily from the photoreceptor layer, while positive IOSs come from inner retinal layers.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.