ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2009
Osteosarcoma presenting as hemorrhagic cerebellar metastasis.
Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 14 citations in OpenAlex.
- Hemorrhagic brain metastasis as the initial presentation of osteosarcoma: a rare case report.Oxford medical case reports · 2025Article
- Brain Metastases from Adult Sarcomas: A Retrospective Cohort Study from the Hellenic Group of Sarcomas and Rare Cancers (HGSRC).Journal of clinical medicine · 2021Article
- Brain metastasis in bone and soft tissue cancers: a review of incidence, interventions, and outcomes.Sarcoma · 2014Review
- A 57-year-old female with a cerebellar mass.Brain pathology (Zurich, Switzerland) · 2011Article
- Central nervous system metastasis from osteosarcoma: Case report and literature review.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation OncologyArticle
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Authors and funding
4 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
purposeOsteosarcoma is the most common malignant bone tumor in children and adolescents. Brain metastasis from osteosarcoma was once uncommon; however, with the advent of chemotherapeutic agents and improved imaging modalities, it has become a more common and recognized finding. Brain metastases are, rarely, the initial presenting symptom, but instead are a late and preterminal event in the disease process. When osteosarcomas manifest in the central nervous system, they tend to occur in the gray-white junction in the anterior circulation akin to other metastatic lesions in the brain. CASE REPORT: The authors report a case of a 16-year-old boy who presented with acute neurological deterioration due to a posterior fossa hemorrhage and was subsequently found to have a primary site localizing to the metaphysis of the right femur with florid metastatic disease.
conclusionsThis is the first case reported in the literature in which an osteosarcoma initially presented as cerebral metastasis in the form of a posterior fossa hemorrhage with a rapidly deteriorating course.
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