ArticleMethods in molecular biology (Clifton, N.J.)2009
Transgenic mouse technology: principles and methods.
Article in Methods in molecular biology (Clifton, N.J.), 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
18 citing papers in PubMed, 40 citations in OpenAlex.
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- Targeting the tumor microenvironment in cholangiocarcinoma to improve immune checkpoint blockade: potential strategies and translational pre-clinical models.Clinical & translational immunology · 2025Review
- Diverse landscape of genetically engineered mouse models: Genomic and molecular insights into prostate cancer.Cancer letters · 2024Review
- Optimization of Large-Scale Adeno-Associated Virus (AAV) Production.Current protocols · 2023Article
- Detection of Transgene Location in the CYP2A13/2B6/2F1-transgenic Mouse Model using Optical Genome Mapping Technology.Drug metabolism and disposition: the biological fate of chemicals · 2023Article
- Spontaneous and Induced Animal Models for Cancer Research.Diagnostics (Basel, Switzerland) · 2020Review
- Review
- Insight intoInternational journal of molecular sciences · 2019Article
- Avian Bioreactor Systems: A Review.Molecular biotechnology · 2018Review
- Molecular regulation of follicle-stimulating hormone synthesis, secretion and action.Journal of molecular endocrinology · 2018Review
- Transgenic Mouse Models in Cancer Research.Frontiers in oncology · 2018Review
- Fshb-iCre mice are efficient and specific Cre deleters for the gonadotrope lineage.Molecular and cellular endocrinology · 2016Article
- Role of human Na,K-ATPase alpha 4 in sperm function, derived from studies in transgenic mice.Molecular reproduction and development · 2015Article
- Redirecting intracellular trafficking and the secretion pattern of FSH dramatically enhances ovarian function in mice.Proceedings of the National Academy of Sciences of the United States of America · 2014Article
- Increased expression of the Na,K-ATPase alpha4 isoform enhances sperm motility in transgenic mice.Biology of reproduction · 2011Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
Introduction of foreign DNA into the mouse germ line is considered a major technical advancement in the fields of developmental biology and genetics. This technology now referred to as transgenic mouse technology has revolutionized virtually all fields of biology and provided new genetic approaches to model many human diseases in a whole animal context. Several hundreds of transgenic lines with expression of foreign genes specifically targeted to desired organelles/cells/tissues have been characterized. Further, the ability to spatio-temporally inactivate or activate gene expression in vivo using the "Cre-lox" technology has recently emerged as a powerful approach to understand various developmental processes including those relevant to molecular endocrinology. In this chapter, we will discuss the principles of transgenic mouse technology, and describe detailed methodology standardized at our institute.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.