ArticleVibrational Spectroscopy2009
Chasing lipids in health and diseases by coherent anti-Stokes Raman scattering microscopy.
Article in Vibrational Spectroscopy, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed.
- Multimodal Raman and Fluorescence Lifetime Imaging: A New Analytical Approach for Resolving Timing-Dependent Metabolic Recovery in Endothelial Dysfunction.Analytical chemistry · 2026Article
- Entangled photons enabled time-frequency-resolved coherent Raman spectroscopy and applications to electronic coherences at femtosecond scale.Light, science & applications · 2022Article
- The histone deacetylase inhibitor, romidepsin, as a potential treatment for pulmonary fibrosis.Oncotarget · 2017Article
- Tracking adipogenic differentiation of skeletal stem cells by label-free chemically selective imaging.Chemical science · 2015Article
- Article
- Quantitative vibrational imaging by hyperspectral stimulated Raman scattering microscopy and multivariate curve resolution analysis.Analytical chemistry · 2013Article
- Piceatannol, natural polyphenolic stilbene, inhibits adipogenesis via modulation of mitotic clonal expansion and insulin receptor-dependent insulin signaling in early phase of differentiation.The Journal of biological chemistry · 2012Article
- Tissue refractive index as marker of disease.Journal of biomedical optics · 2011Article
- Label-free imaging of lipid dynamics using Coherent Anti-stokes Raman Scattering (CARS) and Stimulated Raman Scattering (SRS) microscopy.Current opinion in genetics & development · 2011Review
- Multimodal Nonlinear Optical Microscopy.Laser & photonics reviews · 2011Article
- Nonlinear interferometric vibrational imaging for fast label-free visualization of molecular domains in skin.Analytical and bioanalytical chemistry · 2011Article
- Coherent nonlinear optical imaging: beyond fluorescence microscopy.Annual review of physical chemistry · 2011Review
- Molecular histopathology by spectrally reconstructed nonlinear interferometric vibrational imaging.Cancer research · 2010Article
- Shedding new light on lipid biology with coherent anti-Stokes Raman scattering microscopy.Journal of lipid research · 2010Review
- Imaging with Raman spectroscopy.Current pharmaceutical biotechnology · 2010Review
- Intravital microscopy: a novel tool to study cell biology in living animals.Histochemistry and cell biology · 2010Review
- High speed nonlinear interferometric vibrational analysis of lipids by spectral decomposition.Analytical chemistry · 2010Article
- High-Speed Nonlinear Interferometric Vibrational Imaging of Biological Tissue With Comparison to Raman Microscopy.IEEE journal of quantum electronics · 2009Article
- Intravital microscopy: a practical guide on imaging intracellular structures in live animals.BioarchitectureReview
- Intravital microscopy as a tool to study drug delivery in preclinical studies.Advanced drug delivery reviewsReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
The integration of near IR picosecond pulse excitation, collinear beam geometry, epi-detection, and laser-scanning has produced a coherent anti-Stokes Raman scattering (CARS) microscope with a detection sensitivity of 10(5) vibrational oscillators, sub-micron 3D resolution, and video-rate acquisition speed. The incorporation of spectral detection and other imaging modalities has added versatility to the CARS microscope. These advances allowed sensitive interrogation of biological samples, particularly lipids that have a high density of CH(2) groups. With initial applications to membrane domains, lipid bodies, demyelinating diseases, obesity, and cardiovascular diseases, CARS microscopy is poised to become a powerful bio-imaging tool with the availability of a multifunctional, affordable, easy-to-operate CARS microscope, and the development of CARS endoscopy for in vivo diagnosis.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.