Evidence map›Paper›PMID 19763188›Full record

ArticleNeurocomputing2007

Decoding modulation of the neuromuscular transform.

Estee Stern, Timothy J Fort, Mark W Miller, Charles S Peskin, Vladimir Brezina

Abstract read
In one paragraph

Article in Neurocomputing, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. The neuromuscular transform of the lobster cardiac system explains the opposing effects of a neuromodulator on muscle output.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2013
    Article
  2. Neuromodulatory systems.Frontiers in neural circuits · 2013
    Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Estee SternDepartment of Neuroscience, Mount Sinai School of Medicine, New York, NY.
Timothy J Fort
Mark W Miller
Charles S Peskin
Vladimir Brezina

Funding

Functional dynamics of motor controlR01NS041497 · NINDS · MOUNT SINAI SCHOOL OF MEDICINE OF NYU · PI BREZINA, VLADIMIR · 2001 to 2010
$2.6M
NINDS NIH HHS R01 NS041497
6 · The paper itself

Abstract

When modulators of neuromuscular function alter the motor neuron spike patterns that elicit muscle contractions, it is predicted that they will also retune correspondingly the connecting processes of the neuromuscular transform. Here we confirm this prediction by analyzing data from the cardiac neuromuscular system of the blue crab. We apply a method that decodes the contraction response to the spike pattern in terms of three elementary building-block functions that completely characterize the neuromuscular transform. This method allows us to dissociate modulator-induced changes in the neuromuscular transform from changes in the spike pattern in the normally operating, essentially unperturbed neuromuscular system.

Identifiers

PMID19763188
PMCPMC2745187

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.