Evidence map›Paper›PMID 19763097›Full record

ArticleNature chemical biology2009

Not all quiet on the noise front.

Emma McCullagh, Justin Farlow, Christopher Fuller, Juliet Girard, Joanna Lipinski-Kruszka, Dan Lu, Thomas Noriega, Geoffrey Rollins, Russell Spitzer, Michael Todhunter and 1 more

Abstract read
PubMed Publisher
In one paragraph

Article in Nature chemical biology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Noise decomposition of intracellular biochemical signaling networks using nonequivalent reporters.Proceedings of the National Academy of Sciences of the United States of America · 2014
    Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Emma McCullaghTETRAD Graduate Program, University of California, San Francisco, California, USA.
Justin Farlow
Christopher Fuller
Juliet Girard
Joanna Lipinski-Kruszka
Dan Lu
Thomas Noriega
Geoffrey Rollins
Russell Spitzer
Michael Todhunter
Hana El-Samad

Funding

Systems Biology of Molecular Noise in YeastR01GM086379 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI EL-SAMAD, HANA, MADHANI, HITEN D · 2009 to 2012
$1.1M
NIGMS NIH HHS GM086379
6 · The paper itself

Abstract

Phenotypic diversity exists even within isogenic populations of cells. Such nongenetic individuality may have wide implications for our understanding of many biological processes. The field of study concerned with the investigation of nongenetic individuality, also known as the 'biology of noise', is ripe with exciting scientific opportunities and challenges.

Indexed as

Evolution, MolecularGene ExpressionPhenotypeAgingCell CommunicationStochastic Processes

Identifiers

PMID19763097

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.