ArticleBMC complementary and alternative medicine2009
Termite usage associated with antibiotic therapy: enhancement of aminoglycoside antibiotic activity by natural products of Nasutitermes corniger (Motschulsky 1855).
Article in BMC complementary and alternative medicine, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 43 citations in OpenAlex.
- Wildlife as Food and Medicine in Brazil: A Neglected Zoonotic Risk?Pathogens (Basel, Switzerland) · 2024Review
- Plant-derived secondary metabolites as the main source of efflux pump inhibitors and methods for identification.Journal of pharmaceutical analysis · 2020Review
- Vertebrates as a Bactericidal Agent.EcoHealth · 2018Article
- Farmers' perception of termites in agriculture production and their indigenous utilization in Northwest Benin.Journal of ethnobiology and ethnomedicine · 2017Article
- Edible and medicinal termites: a global overview.Journal of ethnobiology and ethnomedicine · 2015Review
- Phytochemical analysis and modulation of antibiotic activity by Luehea paniculata Mart. & Zucc. (Malvaceae) in multiresistant clinical isolates of Candida spp.BioMed research international · 2015Article
- In vitro antimicrobial and modulatory activity of the natural products silymarin and silibinin.BioMed research international · 2015Article
- The use of the head louse as a remedy for jaundice in Spanish folk medicine: an overview.Journal of ethnobiology and ethnomedicine · 2013Review
- The trade in medicinal animals in northeastern Brazil.Evidence-based complementary and alternative medicine : eCAM · 2012Article
- Natural products from ethnodirected studies: revisiting the ethnobiology of the zombie poison.Evidence-based complementary and alternative medicine : eCAM · 2012Article
- Evaluation of the Antimicrobial Activity of the Decoction of Tropidurus hispidus (Spix, 1825) and Tropidurus semitaeniatus (Spix, 1825) Used by the Traditional Medicine.Evidence-based complementary and alternative medicine : eCAM · 2012Article
- The faunal drugstore: animal-based remedies used in traditional medicines in Latin America.Journal of ethnobiology and ethnomedicine · 2011Review
- Animals to heal animals: ethnoveterinary practices in semiarid region, northeastern Brazil.Journal of ethnobiology and ethnomedicine · 2009Article
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Authors and funding
5 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSeveral species from Insecta are used as remedies. Among these species, the termite Nasutitermes corniger is commonly used in traditional medicine in Northeast Brazil. The present work tests the modifying antibiotic activity of Nasutitermes corniger, a termite used in folk medicine in Northeastern region of Brazil.
methodsChlorpromazine and decocts of N. corniger were collected from two different plant species used in the traditional medicine were tested for their antimicrobial activity against strains of Escherichia coli resistant to aminoglycosides. The growth of two bacterial strains of E. coli was tested using decocts and chlorpromazine alone or associeted with aminogycosides.
resultsThe MIC and MBC values were > or =1024 microg/ml for both strains of E. coli assayed. A significant synergism was observed between both decocts and chlorpromazine when assyed with neomycin. This synergism with neomycin indicates the involvement of an efflux system in the resistance to this aminoglycoside.
conclusionTherefore it is suggested that natural products from N. corniger could be used as a source of zoo-derived natural products with modifying antibiotic activity to aminoglycosides, being a new weapon against the bacterial resistance to antibiotics.
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