Evidence map›Paper›PMID 19761399›Full record

ReviewRegenerative medicine2009

Reclaiming a natural beauty: whole-organ engineering with natural extracellular materials.

Samantha Traphagen, Pamela C Yelick

Abstract readReview
In one paragraph

Review in Regenerative medicine, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Tooth Bioengineering and Regenerative Dentistry.Journal of dental research · 2019
    Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Samantha TraphagenTufts University, Department of Oral & Maxillofacial Pathology, Boston, MA, USA.
Pamela C Yelick

Funding

Dental Stem Cells and Tooth Tissue EngineeringR01DE016132 · NIDCR · TUFTS UNIVERSITY BOSTON · PI YELICK, PAMELA C · 2005 to 2014
$5.5M
NIDCR NIH HHS DE016132NIDCR NIH HHS R01 DE016132
6 · The paper itself

Abstract

The ability to engineer whole organs as replacements for allografts and xenografts is an ongoing pursuit in regenerative medicine. While challenges remain, including systemic tissue integration with angiogenesis, lymphatiogenesis and neurogenesis, ongoing efforts are working to develop novel technologies to produce implantable engineered scaffolds and potentially engineered whole organs. Natural extracellular matrix materials, commonly utilized in vitro, are now being used as effective, natural, acellular allografts, and are being integrated into nanoscale scaffolds and matrices with programmable responsiveness. Based on the significant use of natural scaffolds for tissue regeneration and bioengineering strategies, this review focuses on recent and ongoing efforts to engineer whole organs, such as the tooth, featuring natural extracellular matrix molecules.

Indexed as

Extracellular MatrixExtracellular Matrix ProteinsHumansRegenerationRegenerative MedicineTissue EngineeringTissue ScaffoldsToothExtracellular Matrix Proteins

Identifiers

PMID19761399
PMCPMC3021746

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.