ReviewJournal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract2010
A controversy that has been tough to swallow: is the treatment of achalasia now digested?
Review in Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 30 citations in OpenAlex.
- Laparoscopic Heller myotomy or pneumatic dilatation in achalasia: results of a prospective, randomized study with at least a decade of follow-up.Surgical endoscopy · 2021Trial
- Heller myotomy versus Heller myotomy with Dor fundoplication for achalasia: long-term symptomatic follow-up of a prospective randomized controlled trial.Surgical endoscopy · 2018Trial
- Treatment of achalasia with laparoscopic myotomy or pneumatic dilatation: long-term results of a prospective, randomized study.World journal of surgery · 2015Trial
- Mucosal injury during laparoscopic Heller cardiomyotomy: risk factors and impact on surgical outcomes.Surgery today · 2023Article
- Childhood esophageal achalasia: Case report from Afghanistan with literature review.International journal of surgery case reports · 2022Article
- Article
- Evaluation of timed barium esophagram after per-oral endoscopic myotomy to predict clinical response.Endoscopy international open · 2021Article
- Treatment challenges of sigmoid-shaped esophagus and severe achalasia.Annals of medicine and surgery (2012) · 2021Review
- Mucosal perforation during laparoscopic surgery for achalasia: impact of preoperative pneumatic balloon dilation.Surgical endoscopy · 2017Article
- Esophageal Achalasia: Predictive Value of Preoperative Resting Pressure of LES Correlated with Type of Fundoplication.The Eurasian journal of medicine · 2017Article
- Laparoscopic esophageal myotomy versus pneumatic dilation in the treatment of idiopathic achalasia: a meta-analysis of randomized controlled trials.Clinical and experimental gastroenterology · 2017Article
- Laparoscopic esophagomyotomy for achalasia in children: A review.World journal of gastrointestinal endoscopy · 2016Review
- National outcomes of laparoscopic Heller myotomy: operative complications and risk factors for adverse events.Surgical endoscopy · 2015Article
- Surgical treatment of infantile achalasia: a case report and literature review.Pediatric surgery international · 2014Review
- New endoscopic classification of achalasia for selection of candidates for peroral endoscopic myotomy.World journal of gastroenterology · 2013Article
- Fundoplication after heller myotomy: a retrospective comparison between nissen and dor.The Eurasian journal of medicine · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
Esophageal achalasia is a rare neurodegenerative disease of the esophagus and the lower esophageal sphincter that presents within a spectrum of disease severity related to progressive pathological changes, most commonly resulting in dysphagia. The pathophysiology of achalasia is still incompletely understood, but recent evidence suggests that degeneration of the postganglionic inhibitory nerves of the myenteric plexus could be due to an infectious or autoimmune mechanism, and nitric oxide is the neurotransmitter affected. Current treatment of achalasia is directed at palliation of symptoms. Therapies include pharmacological therapy, endoscopic injection of botulinum toxin, endoscopic dilation, and surgery. Until the late 1980s, endoscopic dilation was the first line of therapy. The advent of safe and effective minimally invasive surgical techniques in the early 1990s paved the way for the introduction of laparoscopic myotomy. This review will discuss the most up-to-date information regarding the pathophysiology, diagnosis, and treatment of achalasia, including a historical perspective. The laparoscopic Heller myotomy with partial fundoplication performed at an experienced center is currently the first line of therapy because it offers a low complication rate, the most durable symptom relief, and the lowest incidence of postoperative gastroesophageal reflux.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.