ArticleEuropean radiology2010
Coronary calcium score and computed tomography coronary angiography in high-risk asymptomatic subjects: assessment of diagnostic accuracy and prevalence of non-obstructive coronary artery disease.
Article in European radiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 4 of them syntheses that pooled it.
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Who cites it
21 citing papers in PubMed, 4 syntheses or guidelines pooled it, 43 citations in OpenAlex.
- The diagnostic performance of coronary artery angiography with 64-MSCT and post 64-MSCT: systematic review and meta-analysis.PloS one · 2014Pooled it
- Diagnostic performance of coronary CT angiography for stenosis detection according to calcium score: systematic review and meta-analysis.European radiology · 2012Pooled it
- Clinical indications for cardiac computed tomography. From the Working Group of the Cardiac Radiology Section of the Italian Society of Medical Radiology (SIRM).La Radiologia medica · 2012Guideline
- Korean guidelines for the appropriate use of cardiac CT.Korean journal of radiologyGuideline
- Prognostic Value of Coronary Calcium Score in Asymptomatic Individuals: A Systematic Review.Journal of clinical medicine · 2022Review
- Stable ischemic heart disease: re-appraisal of coronary revascularization criteria in the light of contemporary evidence.Cardiovascular diagnosis and therapy · 2020Review
- Value of cardiac computed tomography angiography in pre-operative assessment of infective endocarditis.Journal of cardiothoracic surgery · 2019Article
- Utility of cardiac computed tomography scanning in the diagnosis and pre-operative evaluation of patients with infective endocarditis.The international journal of cardiovascular imaging · 2018Article
- Relationship between coronary atherosclerosis in coronary computed tomography angiography and serum vitamin D level.Osteoporosis and sarcopenia · 2017Article
- Diagnostic efficacy of vessel specific coronary calcium score in detection of coronary artery stenosis.Iranian Red Crescent medical journal · 2014Article
- Prognostic value of coronary artery calcium score in patients with stable angina pectoris after percutaneous coronary intervention.Journal of geriatric cardiology : JGC · 2014Article
- Noncalcified coronary plaque volumes in healthy people with a family history of early onset coronary artery disease.Circulation. Cardiovascular imaging · 2014Article
- Coronary calcium scoring: are the results comparable to computed tomography coronary angiography for screening coronary artery disease in a South Asian population?BMC research notes · 2013Article
- Rationale, design and methods of CTCA-PRORECAD (Computed Tomography Coronary Angiography Prognostic Registry for Coronary Artery Disease): a multicentre and multivendor registry.La Radiologia medica · 2013Article
- Prognostic value of cardiovascular CT: is coronary artery calcium screening enough? The added value of CCTA.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2012Article
- Diagnosis of coronary artery disease in persons with diabetes mellitus.Current diabetes reports · 2012Article
- Computed tomography coronary angiography in the selection of outlier patients: a feasibility report.La Radiologia medica · 2012Article
- Diagnostic accuracy of 64-slice computed tomography coronary angiography in a large population of patients without revascularisation: registry data on the comparison between male and female population.La Radiologia medica · 2012Article
- Diagnostic accuracy of 64-slice computed tomography coronary angiography in a large population of patients without revascularisation: registry data in NSTEMI acute coronary syndrome and influence of gender and risk factors.La Radiologia medica · 2011Article
- Diagnostic accuracy of 64-slice computed tomography coronary angiography in a large population of patients without revascularisation: registry data on the impact of calcium score.La Radiologia medica · 2011Article
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Authors and funding
11 authors at 4 institutions in 2 countries.
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Abstract
objectivesThe aim of the study was to compare the coronary artery calcium score (CACS) and computed tomography coronary angiography (CTCA) for the assessment of non-obstructive/obstructive coronary artery disease (CAD) in high-risk asymptomatic subjects.
methodsTwo hundred and thirteen consecutive asymptomatic subjects (113 male; mean age 53.6 +/- 12.4 years) with more than one risk factor and an inconclusive or unfeasible non-invasive stress test result underwent CACS and CTCA in an outpatient setting. All patients underwent conventional coronary angiography (CAG). Data from CACS (threshold for positive image: Agatston score 1/100/1,000) and CTCA were compared with CAG regarding the degree of CAD (non-obstructive/obstructive; </>or=50% lumen reduction).
resultsThe mean calcium score was 151 +/- 403 and the prevalence of obstructive CAD was 17% (8% one-vessel and 10% two-vessel disease). Per-patient sensitivity, specificity, positive and negative predictive values of CACS were: 97%, 75%, 45%, and 100%, respectively (Agatston >or=1); 73%, 90%, 60%, and 94%, respectively (Agatston >or=100); 30%, 98%, 79%, and 87%, respectively (Agatston >or=1,000). Per-patient values for CTCA were 100%, 98%, 97%, and 100%, respectively (p < 0.05). CTCA detected 65% prevalence of all CAD (48% non-obstructive), while CACS detected 37% prevalence of all CAD (21% non-obstructive) (p < 0.05).
conclusionCACS proved inadequate for the detection of obstructive and non-obstructive CAD compared with CTCA. CTCA has a high diagnostic accuracy for the detection of non-obstructive and obstructive CAD in high-risk asymptomatic patients with inconclusive or unfeasible stress test results.
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