ReviewIntensive care medicine2009
Determinants of regional ventilation and blood flow in the lung.
Review in Intensive care medicine, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 59 citations in OpenAlex.
- Effect of time and body position on ventilation in premature infants.Pediatric research · 2016Trial
- Changes in mucin expression in the lungs of infant piglets following cardiopulmonary bypass with deep hypothermic circulatory arrest.Journal of investigative medicine : the official publication of the American Federation for Clinical Research · 2026Article
- Regional Pulmonary Involvement in Bronchiolitis: Insights From Lung Ultrasound.Pediatric pulmonology · 2025Article
- Imaging the pulmonary vasculature in acute respiratory distress syndrome.Nitric oxide : biology and chemistry · 2024Review
- Lung endothelium, tau, and amyloids in health and disease.Physiological reviews · 2024Review
- Prognostic Value of the Area of Lung Involved in Severe and Non-Severe Bronchiolitis: An Observational, Ultrasound-Based Study.Journal of clinical medicine · 2023Article
- Perioperative Pulmonary Atelectasis: Part I. Biology and Mechanisms.Anesthesiology · 2022Review
- PPV May Be a Starting Point to Achieve Circulatory Protective Mechanical Ventilation.Frontiers in medicine · 2021Review
- Ventilation/Perfusion Matching: Of Myths, Mice, and Men.Physiology (Bethesda, Md.) · 2019Review
- Extracellular matrix in lung development, homeostasis and disease.Matrix biology : journal of the International Society for Matrix Biology · 2018Review
- Correlation of Regional Lung Ventilation and Gas Transfer to Red Blood Cells: Implications for Functional-Avoidance Radiation Therapy Planning.International journal of radiation oncology, biology, physics · 2018Article
- Physiology for the pulmonary functional imager.European journal of radiology · 2017Review
- Single-energy computed tomography-based pulmonary perfusion imaging: Proof-of-principle in a canine model.Medical physics · 2016Article
- Variability of the Sheep Lung Microbiota.Applied and environmental microbiology · 2016Article
- Article
- Echocardiographic evaluation of pulmonary venous blood flow and cardiac function changes during one-lung ventilation.International journal of clinical and experimental medicine · 2015Article
- The lack of a big picture in tuberculosis: the clinical point of view, the problems of experimental modeling and immunomodulation. The factors we should consider when designing novel treatment strategies.Frontiers in microbiology · 2014Review
- Probing the regional distribution of pulmonary gas exchange through single-breath gas- and dissolved-phase 129Xe MR imaging.Journal of applied physiology (Bethesda, Md. : 1985) · 2013Article
- A computational model of the topographic distribution of ventilation in healthy human lungs.Journal of theoretical biology · 2012Article
- Distribution of Pneumocystis jirovecii in lungs from colonized COPD patients.Diagnostic microbiology and infectious disease · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The principles of ventilation and perfusion distribution in the lung form the foundation of pulmonary physiology and remain cornerstones in caring for critically ill patients. Due to improved imaging technologies with greater spatial resolution, our understanding of the determinants of local ventilation and blood flow have evolved over the past five decades. This review provides a brief history of how the concepts governing regional ventilation and perfusion have developed and presents the most recent studies that are shaping new perspectives on the determinants of ventilation and perfusion. How these new principles apply to acute lung injury and gas exchange in the intensive care unit(ICU) are reviewed.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.