Evidence map›Paper›PMID 19759880›Full record

ArticleClinics (Sao Paulo, Brazil)2009

Quality of life among HIV-infected patients in Brazil after initiation of treatment.

Lorenza Nogueira Campos, Cibele Comini César, Mark Drew Crosland Guimarães

Abstract read
In one paragraph

Article in Clinics (Sao Paulo, Brazil), 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  20. Quality of life, anxiety and depression in patients with HIV/AIDS who present poor adherence to antiretroviral therapy: a cross-sectional study in Salvador, Brazil.The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Lorenza Nogueira CamposDepartment of Preventive and Social Medicine, School of Medicine, Federal University of Minas Gerais, Belo Horizonte/MG, Brazil. lorenzanc@gmail.com
Cibele Comini César
Mark Drew Crosland Guimarães

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionDespite improvement in clinical treatment for HIV-infected patients, the impact of antiretroviral therapy on the overall quality of life has become a major concern.

objectiveTo identify factors associated with increased levels of self-reported quality of life among HIV-infected patients after four months of antiretroviral therapy.

methodsPatients were recruited at two public health referral centers for AIDS, Belo Horizonte, Brazil, for a prospective adherence study. Patients were interviewed before initiating treatment (baseline) and after one and four months. Quality of life was assessed using a psychometric instrument, and factors associated with good/very good quality of life four months after the initiation of antiretroviral therapy were assessed using a cross-sectional approach. Logistic regression was used for analysis.

resultsOverall quality of life was classified as 'very good/good' by 66.4% of the participants four months after initiating treatment, while 33.6% classified it as 'neither poor nor good/poor/very poor'. Logistic regression indicated that >8 years of education, none/mild symptoms of anxiety and depression, no antiretroviral switch, lower number of adverse reactions and better quality of life at baseline were independently associated with good/very good quality of life over four months of treatment.

conclusionsOur results highlight the importance of modifiable factors such as psychiatric symptoms and treatment-related variables that may contribute to a better quality of life among patients initiating treatment. Considering that poor quality of life is related to non-adherence to antiretroviral therapy, careful clinical monitoring of these factors may contribute to ensuring the long-term effectiveness of antiretroviral regimens.

Indexed as

AdultAnti-HIV AgentsAnxietyBrazilDepressionFemaleHIV InfectionsHumansMalePatient ComplianceProspective StudiesQuality of LifeSocioeconomic FactorsAnti-HIV AgentsAdverse reactionsAntiretroviral therapyAntiretroviral therapy switchAnxietyDepression

Identifiers

PMID19759880
PMCPMC2745298

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.