Evidence map›Paper›PMID 19759545›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2010

Long-term morbidities associated with vocal cord paralysis after surgical closure of a patent ductus arteriosus in extremely low birth weight infants.

J R Benjamin, P B Smith, C M Cotten, J Jaggers, R F Goldstein, W F Malcolm

Open access · greenAbstract read
In one paragraph

Article in Journal of perinatology : official journal of the California Perinatal Association, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 2 pooled it
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 2 syntheses or guidelines pooled it, 124 citations in OpenAlex.

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  7. Review
  8. [The consensus among experts on the diagnosis and treatment of pediatric vocal cord paralysis].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2023
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

J R BenjaminDivision of Neonatal-Perinatal Medicine, Department of Pediatrics, Jean and George Brumley Jr. Neonatal Perinatal Research Institute, Duke University Medical Center, Durham, NC 27710, USA.
P B Smith
C M Cotten
J Jaggers
R F Goldstein
W F Malcolm
Duke University Hospital · USDuke Medical Center · US

Funding

NICHD Cooperative Multicenter Neonatal Research NetworkU10HD040492 · NICHD · DUKE UNIVERSITY · PI COTTEN, CHARLES MICHAEL · 2001 to 2015
$5.4M
North Carolina Clinical CenterUG1HD040492 · NICHD · DUKE UNIVERSITY · PI CHARLES Michael COTTEN, Matthew Laughon · 2016 to 2026
$3.4M
PHARMACOKINETICS OF ANTIMICROBIAL AGENTS IN HIGH RISK INFANTSK23HD060040 · NICHD · DUKE UNIVERSITY · PI SMITH, PHILLIP BRIAN · 2009 to 2012
$445k
NICHD NIH HHS K23 HD060040NICHD NIH HHS U10 HD040492NICHD NIH HHS UG1 HD040492
6 · The paper itself

Abstract

objectiveDetermine associations between left vocal cord paralysis (LVCP) and poor respiratory, feeding and/or developmental outcomes in extremely low birth weight (ELBW) infants following surgical closure of a patent ductus arteriosus (PDA). STUDY

designELBW infants who underwent PDA ligation between January 2004 and December 2006 were identified. We compared infants with and without LVCP following ligation to determine relationships between LVCP and respiratory morbidities, feeding and growth difficulties and neurodevelopmental impairment at 18 to 22-month follow-up. Student's t-test, Fisher's exact test and multivariable regression analyses were used to determine associations.

resultIn all, 60 ELBW infants with a mean gestational age of 25 weeks and mean birth weight of 725 g had a PDA surgically closed. Twenty-two of 55 survivors (40%) were diagnosed with LVCP post-operatively. Infants with LVCP were significantly more likely to develop bronchopulmonary dysplasia (82 vs 39%, P=0.002), reactive airway disease (86 vs 33%, P<0.0001), or need for gastrostomy tube (63 vs 6%, P<0.0001).

conclusionLVCP as a complication of surgical ductal ligation in ELBW infants is associated with persistent respiratory and feeding problems. Direct laryngoscopy should be considered for all infants who experience persistent respiratory and/or feeding difficulties following PDA ligation.

Indexed as

Recurrent Laryngeal Nerve InjuriesBronchopulmonary DysplasiaDevelopmental DisabilitiesDuctus Arteriosus, PatentEnteral NutritionFemaleFollow-Up StudiesGastroesophageal RefluxHumansInfantInfant, Extremely Low Birth WeightInfant, NewbornLigationMalePostoperative ComplicationsVocal Cord Paralysis

Identifiers

PMID19759545
PMCPMC2878380
OpenAlexW2016470664

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.