Evidence map›Paper›PMID 19756982›Full record

ArticleJournal of fluorescence2010

Effective critical micellar concentration of a zwitterionic detergent: a fluorimetric study on n-dodecyl phosphocholine.

Pasquale Palladino, Filomena Rossi, Raffaele Ragone

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of fluorescence, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Complex Self-Organization inLangmuir : the ACS journal of surfaces and colloids · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Detergent-mediated protein aggregation.Chemistry and physics of lipids · 2013
    Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Pasquale PalladinoDipartimento delle Scienze Biologiche & C.I.R.Pe.B., Università Federico II, via Mezzocannone 16, 80134, Naples, Italy.
Filomena Rossi
Raffaele Ragone

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We have investigated the effect of ionic strength on the aggregation behavior of n-dodecyl phosphocholine. On the basis of the classical Corrin-Harkins relation, the critical micellar concentration of this detergent decreases with a biphasic trend on lithium chloride addition. It is nearly constant below 150 mM salt, with a mean value of 0.91 mM, whereas it undergoes a dramatic 80-fold decrease in 7 M LiCl. Such a drop in the critical micellar concentration could be explained by the effect of salting out and the implication of phosphocholine head groups on the organization of surrounding water. Knowledge of the effective critical micellar concentration of n-dodecyl phosphocholine could be useful in the purification of membrane proteins in non-denaturing conditions.

Indexed as

MicellesAnilino NaphthalenesulfonatesDetergentsFluorescent DyesFluorometryLithium ChlorideOsmolar ConcentrationPhosphorylcholineWater1-anilino-8-naphthalenesulfonateAnilino NaphthalenesulfonatesDetergentsdodecylphosphocholineFluorescent DyesLithium ChlorideMicellesPhosphorylcholineWater

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.