Trial reportPsychopharmacology2009
Alcohol-induced increases in smoking behavior for nicotinized and denicotinized cigarettes in men and women.
Trial report in Psychopharmacology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
39 citing papers in PubMed, 1 synthesis or guideline pooled it, 67 citations in OpenAlex.
- Inhalation of Alcohol Vapor: Measurement and Implications.Alcoholism, clinical and experimental research · 2017Pooled it
- Combined varenicline and naltrexone treatment reduces smoking topography intensity in heavy-drinking smokers.Pharmacology, biochemistry, and behavior · 2015Trial
- Naltrexone improves quit rates, attenuates smoking urge, and reduces alcohol use in heavy drinking smokers attempting to quit smoking.Alcoholism, clinical and experimental research · 2014Trial
- Brain regions affected by impaired control modulate responses to alcohol and smoking cues.Journal of studies on alcohol and drugs · 2014Trial
- Length of smoking deprivation moderates the effects of alcohol administration on urge to smoke.Addictive behaviors · 2014Trial
- Nicotine interactions with low-dose alcohol: pharmacological influences on smoking and drinking motivation.Journal of abnormal psychology · 2013Trial
- Pilot randomized trial on mindfulness training for smokers in young adult binge drinkers.BMC complementary and alternative medicine · 2013Trial
- Alcohol attenuates amygdala-frontal connectivity during processing social signals in heavy social drinkers: a preliminary pharmaco-fMRI study.Psychopharmacology · 2013Trial
- Alternative substance paradigm: effectiveness of beverage blinding and effects on acute alcohol responses.Experimental and clinical psychopharmacology · 2012Trial
- Sex differences in stimulus expectancy and pharmacologic effects of a moderate dose of alcohol on smoking lapse risk in a laboratory analogue study.Psychopharmacology · 2012Trial
- Preliminary findings on the interactive effects of IV ethanol and IV nicotine on human behavior and cognition: a laboratory study.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2012Trial
- Neural substrates of alcohol-induced smoking urge in heavy drinking nondaily smokers.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2010Trial
- Alcohol dependence and consumption status are related to smoking status: A cross-sectional study of data from the Japan Society and New Tobacco Internet Survey 2023.Tobacco prevention & cessation · 2025Article
- Dietary Habits, Nutrition Intake, and Alcohol Consumption Based on Types of Smoking and Smoking Status: A Cross-Sectional Study.Nutrients · 2024Article
- Enhancing translation: A need to leverage complex preclinical models of addictive drugs to accelerate substance use treatment options.Pharmacology, biochemistry, and behavior · 2024Review
- Synthetic contraceptive hormones occlude the ability of nicotine to reduce ethanol consumption in ovary-intact female rats.Drug and alcohol dependence · 2023Article
- Addiction-Related Outcomes of Nicotine and Alcohol Co-use: New Insights Following the Rise in Vaping.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2022Review
- Racial Differences in the Association Between Alcohol Drinking and Cigarette Smoking: Preliminary Findings From an Alcohol Research Program.Alcohol and alcoholism (Oxford, Oxfordshire) · 2022Article
- Association of Alcohol Consumption and Ideal Cardiovascular Health Among South Asians: The Mediators of Atherosclerosis in South Asians Living in America (MASALA) Study.Alcoholism, clinical and experimental research · 2020Article
- An overview of alcohol and tobacco/nicotine interactions in the human laboratory.The American journal of drug and alcohol abuse · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
introductionAlcohol has been shown to increase smoking urges and smoking behavior. However, alcohol's effects on specific components of smoking behavior for nicotine versus non-nicotine factors and potential sex differences in this response have not been investigated.
methodsForty-two young male and female non-dependent, heavy social drinking smokers participated in two double-blind laboratory sessions. They were randomized to either an alcohol (0.8 g/kg; n = 29) or placebo (n = 13) beverage pre-administration group. After beverage consumption, they were assessed for smoking urges and then given the opportunity to smoke cigarettes which were either all nicotinized (0.6 mg/cigarette) or denicotinized (< or =0.05 mg/cigarette) over a 3-h period; smoking behavior was quantified by a smoking topography device. Subjects took standardized puffs of the session's cigarette both before and after beverage administration to provide a reference when making future smoking choices.
resultsAlcohol, compared with placebo beverage, increased both men's and women's smoking urge, as well as subjective ratings of smoking reference puffs for either nicotinized or denicotinized cigarettes. In terms of smoking choice behavior, regardless of cigarette type, alcohol (>placebo) increased men's smoking behavior, including puff count, volume, and duration. In contrast, for women, smoking topography measures did not differ between alcohol and placebo conditions. DISCUSSION: In summary regardless of nicotine content, in men, alcohol increased smoking urge and behavior, whereas in women, alcohol increased smoking urge but did not increase smoking behavior. These results indicate that the mechanisms underlying co-use of alcohol and tobacco in women may be more complex than in men.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.