ArticleExpert review of clinical immunology2008
Innate immunity to influenza virus: implications for future therapy.
Article in Expert review of clinical immunology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed.
- Review
- Review
- The global burden of swine influenza and its mitigation.Open veterinary journal · 2025Review
- A novel lncRNA DFRV plays a dual function in influenza A virus infection.Frontiers in microbiology · 2023Article
- A Systems Biology Workflow for Drug and Vaccine Repurposing: Identifying Small-Molecule BCG Mimics to Reduce or Prevent COVID-19 Mortality.Pharmaceutical research · 2020Article
- Regulation of Host Immune Responses against Influenza A Virus Infection by Mitogen-Activated Protein Kinases (MAPKs).Microorganisms · 2020Review
- Natural Killer Cells Dampen the Pathogenic Features of Recall Responses to Influenza Infection.Frontiers in immunology · 2020Article
- The dual role of innate immunity during influenza.Biomedical journal · 2019Review
- Integrated Omics and Computational Glycobiology Reveal Structural Basis for Influenza A Virus Glycan Microheterogeneity and Host Interactions.Molecular & cellular proteomics : MCP · 2016Article
- Influenza Virus Targets Class I MHC-Educated NK Cells for Immunoevasion.PLoS pathogens · 2016Article
- Emerging Infections of CNS: Avian Influenza A Virus, Rift Valley Fever Virus and Human Parechovirus.Brain pathology (Zurich, Switzerland) · 2015Review
- The human cathelicidin LL-37 inhibits influenza A viruses through a mechanism distinct from that of surfactant protein D or defensins.The Journal of general virology · 2013Article
- Rapid differentiation of monocytes into type I IFN-producing myeloid dendritic cells as an antiviral strategy against influenza virus infection.Journal of immunology (Baltimore, Md. : 1950) · 2012Article
- A unique sugar-binding site mediates the distinct anti-influenza activity of pig surfactant protein D.The Journal of biological chemistry · 2012Article
- Hapivirins and diprovirins: novel θ-defensin analogs with potent activity against influenza A virus.Journal of immunology (Baltimore, Md. : 1950) · 2012Article
- Explaining rapid reinfections in multiple-wave influenza outbreaks: Tristan da Cunha 1971 epidemic as a case study.Proceedings. Biological sciences · 2011Article
- GM-CSF modulates pulmonary resistance to influenza A infection.Antiviral research · 2011Article
- Galectin-1 binds to influenza virus and ameliorates influenza virus pathogenesis.Journal of virology · 2011Article
- Introduction of N-linked glycans in the lectin domain of surfactant protein D: impact on interactions with influenza A viruses.The Journal of biological chemistry · 2011Article
- Population modeling of influenza A/H1N1 virus kinetics and symptom dynamics.Journal of virology · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Innate immunity is critical in the early containment of influenza virus infection. The innate response is surprisingly complex. A variety of soluble innate inhibitors in respiratory secretions provide an initial barrier to infection. Dendritic cells, phagocytes and natural killer cells mediate viral clearance and promote further innate and adaptive responses. Toll-like receptors 3 and 7 and cytoplasmic RNA sensors are critical for activating these responses. In general, the innate response restricts viral replication without injuring the lung; however, the 1918 pandemic and H5N1 strains cause more profound, possibly harmful, innate responses. In this review, we discuss the implications of burgeoning knowledge of innate immunity for therapy of influenza.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.