Evidence map›Paper›PMID 19756010›Full record

ReviewNature reviews. Microbiology2009

Engineering for biofuels: exploiting innate microbial capacity or importing biosynthetic potential?

Hal Alper, Gregory Stephanopoulos

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Microbiology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 120 papers.

0numbers the graph read from it
0cells of the map it votes in
120citing papers in PubMed
15.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

120 citing papers in PubMed, 388 citations in OpenAlex.

  1. Article
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  3. Article
  4. Review
  5. Applied microbiology of the phyllosphere.Applied microbiology and biotechnology · 2024
    Review
  6. Article
  7. Article
  8. Article
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  11. Review
  12. Review
  13. Review
  14. Article
  15. Review
  16. Article
  17. Factors affecting yeast ethanol tolerance and fermentation efficiency.World journal of microbiology & biotechnology · 2020
    Review
  18. Article
  19. Review
  20. Article

60 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Hal AlperDepartment of Chemical Engineering, The University of Texas at Austin, 1 University Station, C0400, Austin, Texas 78712, USA.
Gregory Stephanopoulos
Massachusetts Institute of Technology · USThe University of Texas at Austin · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The ideal microorganism for biofuel production will possess high substrate utilization and processing capacities, fast and deregulated pathways for sugar transport, good tolerance to inhibitors and product, and high metabolic fluxes and will produce a single fermentation product. It is unclear whether such an organism will be engineered using a native, isolated strain or a recombinant, model organism as the starting point. The choice between engineering natural function and importing biosynthetic capacity is affected by current progress in metabolic engineering and synthetic biology. This Review highlights some of the factors influencing the above decision, in light of current advances.

Indexed as

Bioelectric Energy SourcesGenetic EngineeringAnimalsBacteriaBiological ProductsFermentationFungiHumansSystems BiologyBiological Products

Identifiers

PMID19756010
OpenAlexW2018994057

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.