Evidence map›Paper›PMID 19755495›Full record

Trial reportJournal of pediatric psychology2010

Predictors of medication adherence in high risk youth of color living with HIV.

Karen E Macdonell, Sylvie Naar-King, Debra A Murphy, Jeffrey T Parsons, Gary W Harper

Registry-linked trialAbstract readClinical Trial
In one paragraph

Trial report in Journal of pediatric psychology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02459678 (ART Readiness in HIV-infected Pregnant Women), which is not on this map. Cited by 51 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02459678 nacompletednot on this mapstarted 2015, after this paper: background citation

ART Readiness in HIV-infected Pregnant Women: From Formative Qualitative Research to Individual Randomized Trial

TypeinterventionalSponsorUniversity of North Carolina, Chapel HillRan2015 to 2018Enrolled454ConditionsHuman Immunodeficiency VirusArmsEnhanced Adherence Package, Standard of Care
3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Karen E MacdonellWayne State University, Pediatric Prevention Research Center, Hutzel Building Suite w534, 4707 St. Antoine, Detroit, MI 48201, USA. kkolmodin@med.wayne.edu
Sylvie Naar-King
Debra A Murphy
Jeffrey T Parsons
Gary W Harper

Funding

Adol. Medicine Trials Network for HIV/AIDS InterventionsU01HD040474 · NICHD · WESTAT, INC. · PI HARRIS, DONALD ROBERT · 2001 to 2016
$114.4M
LEADERSHIP GROUP FOR ADOLESCENT MEDICINE TRIALS NETWORKU01HD040533 · NICHD · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI WILSON, CRAIG M · 2001 to 2016
$76.4M
NICHD NIH HHS U01 HD040474NICHD NIH HHS U01 HD040533NICHD NIH HHS U01-HD040533
6 · The paper itself

Abstract

objectiveTo test predictors of medication adherence in high-risk racial or ethnic minority youth living with HIV (YLH) using a conceptual model of social cognitive predictors including a continuous measure of motivational readiness.

methodsYouth were participants in a multi-site clinical trial examining the efficacy of a motivational intervention. Racial-minority YLH (primarily African American) who were prescribed antiretroviral medication were included (N = 104). Data were collected using computer-assisted personal interviewing method via an Internet-based application and questionnaires.

resultsUsing path analysis with bootstrapping, most youth reported suboptimal adherence, which predicted higher viral load. Higher motivational readiness predicted optimal adherence, and higher social support predicted readiness. Decisional balance was indirectly related to adherence.

conclusionsThe model provided a plausible framework for understanding adherence in this population. Culturally competent interventions focused on readiness and social support may be helpful for improving adherence in YLH.

Indexed as

MotivationAdolescentAnti-Retroviral AgentsBlack or African AmericanChi-Square DistributionFemaleHIV InfectionsHIV SeropositivityHumansMaleMedication AdherenceSocial SupportSurveys and QuestionnairesViral LoadYoung AdultAnti-Retroviral Agents

Identifiers

PMID19755495
PMCPMC2889251

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.