Evidence map›Paper›PMID 19754934›Full record

ArticleCardiovascular diabetology2009

Blood pressure control and components of the metabolic syndrome: the GOOD survey.

Walter Zidek, Lisa Naditch-Brûlé, Stefano Perlini, Csaba Farsang, Sverre E Kjeldsen

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in Cardiovascular diabetology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 53 citations in OpenAlex.

  1. Pooled it
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  7. A Longitudinal Assessment of Metabolic Syndrome.Journal of clinical medicine · 2025
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  13. Uncontrolled hypertension in patients with type 2 diabetes: What are the correlates?Journal of clinical hypertension (Greenwich, Conn.) · 2021
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  16. Association between a polymorphic poly-T repeat sequence in the promoter of the somatostatin gene and hypertension.Hypertension research : official journal of the Japanese Society of Hypertension · 2016
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  17. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 4 countries.

Walter ZidekMedizinische Klinik IV (Endocrinology and Nephrology), Charité, Berlin, Germany. walter.zidek@charite.de
Lisa Naditch-Brûlé
Stefano Perlini
Csaba Farsang
Sverre E Kjeldsen
Charité - Universitätsmedizin Berlin · DEIstituti di Ricovero e Cura a Carattere Scientifico · ITSanofi (France) · FRUllevål Sykehusapotek · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe GOOD (Global Cardiometabolic Risk Profile in Patients with Hypertension Disease) survey showed that blood pressure control was significantly worse in hypertensive patients with metabolic syndrome and/or diabetes mellitus than in those with essential hypertension only. This analysis aimed to investigate which components of the metabolic syndrome are primarily associated with poor blood pressure control.

methodsThe GOOD survey was designed as an observational cross-sectional survey in 12 European countries to assess the cardiometabolic risk profile in patients with essential hypertension. Investigators were randomly selected from a list of general practitioners (70% of investigators) and a list of specialists such as internists, cardiologists and hypertension specialists (30% of investigators). Data from 3,280 outpatients with hypertension, aged at least 30 years who were receiving antihypertensive treatment or had newly diagnosed hypertension according to the European Society of Hypertension and the European Society of Cardiology criteria, were included in the analyses. Blood pressure control, body mass index (BMI), waist circumference, serum triglycerides, total and high density lipoprotein (HDL) cholesterol measurements were compared in patients with diabetes mellitus and metabolic syndrome, with diabetes mellitus only, with metabolic syndrome only, and with neither metabolic syndrome nor diabetes mellitus.

resultsThe highest blood pressure values were found in patients with metabolic syndrome with or without diabetes mellitus. Blood pressure was significantly lower in patients with diabetes mellitus only. The highest BMI, waist circumference and serum triglycerides, and the lowest HDL cholesterol levels among the groups studied occurred in patients with metabolic syndrome, either with or without diabetes mellitus.

conclusionAmong the components of the metabolic syndrome, it is not impaired glucose tolerance which is associated with the poor response to antihypertensive treatment. Instead, visceral obesity and dyslipidemia components of the metabolic syndrome, i.e. hypertriglyceridemia and low HDL cholesterol levels, are associated with resistance to antihypertensive treatment.

Indexed as

Blood PressureAdultAgedAntihypertensive AgentsBody Mass IndexComorbidityCreatinineCross-Sectional StudiesDiabetes MellitusDrug ResistanceEuropeFemaleHabitsHealth SurveysHumansHypertensionAntihypertensive AgentsCreatinineLipids

Identifiers

PMID19754934
PMCPMC2757016
OpenAlexW2103481045

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.