ArticleFrontiers in neural circuits2009
Sub-Millisecond Firing Synchrony of Closely Neighboring Pyramidal Neurons in Hippocampal CA1 of Rats During Delayed Non-Matching to Sample Task.
Article in Frontiers in neural circuits, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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23 citing papers in PubMed.
- Multi-synaptic boutons are a feature of CA1 hippocampal connections in the stratum oriens.Cell reports · 2023Article
- The hearing hippocampus.Progress in neurobiology · 2022Review
- Multiple Approaches to the Investigation of Cell Assembly in Memory Research-Present and Future.Frontiers in systems neuroscience · 2018Review
- Regulation of Cortical Dynamic Range by Background Synaptic Noise and Feedforward Inhibition.Cerebral cortex (New York, N.Y. : 1991) · 2016Article
- Episodic-like memory trace in awake replay of hippocampal place cell activity sequences.eLife · 2015Article
- Millisecond timescale synchrony among hippocampal neurons.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2014Article
- Volitional enhancement of firing synchrony and oscillation by neuronal operant conditioning: interaction with neurorehabilitation and brain-machine interface.Frontiers in systems neuroscience · 2014Review
- Brain-machine interfaces can accelerate clarification of the principal mysteries and real plasticity of the brain.Frontiers in systems neuroscience · 2014Article
- Synchronous firing of antennal-lobe projection neurons encodes the behaviorally effective ratio of sex-pheromone components in male Manduca sexta.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2013Article
- Article
- Oscillatory interaction between amygdala and hippocampus coordinates behavioral modulation based on reward expectation.Frontiers in behavioral neuroscience · 2013Article
- A possible role of astrocytes in contextual memory retrieval: An analysis obtained using a quantitative framework.Frontiers in computational neuroscience · 2013Article
- Schaffer-specific local field potentials reflect discrete excitatory events at gamma frequency that may fire postsynaptic hippocampal CA1 units.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2012Article
- Sound sensitivity of neurons in rat hippocampus during performance of a sound-guided task.Journal of neurophysiology · 2012Article
- Auditory stimuli elicit hippocampal neuronal responses during sleep.Frontiers in systems neuroscience · 2012Article
- State-space analysis of time-varying higher-order spike correlation for multiple neural spike train data.PLoS computational biology · 2012Article
- Article
- Submillisecond firing synchrony between different subtypes of cortical interneurons connected chemically but not electrically.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2011Article
- Task-dependent and independent synchronous activity of monkey hippocampal neurons in real and virtual translocation.Frontiers in behavioral neuroscience · 2011Article
- Neighboring Pallidal Neurons Do Not Exhibit more Synchronous Oscillations than Remote Ones in the MPTP Primate Model of Parkinson's Disease.Frontiers in systems neuroscience · 2011Article
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2 authors.
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Abstract
Firing synchrony among neurons is thought to play functional roles in several brain regions. In theoretical analyses, firing synchrony among neurons within sub-millisecond precision is feasible to convey information. However, little is known about the occurrence and the functional significance of the sub-millisecond synchrony among closely neighboring neurons in the brain of behaving animals because of a technical issue: spikes simultaneously generated from closely neighboring neurons are overlapped in the extracellular space and are not easily separated. As described herein, using a unique spike sorting technique based on independent component analysis together with extracellular 12-channel multi-electrodes (dodecatrodes), we separated such overlapping spikes and investigated the firing synchrony among closely neighboring pyramidal neurons in the hippocampal CA1 of rats during a delayed non-matching to sample task. Results showed that closely neighboring pyramidal neurons in the hippocampal CA1 can co-fire with sub-millisecond precision. The synchrony generally co-occurred with the firing rate modulation in relation to both internal (retention and comparison) and external (stimulus input and motor output) events during the task. However, the synchrony occasionally occurred in relation to stimulus inputs even when rate modulation was clearly absent, suggesting that the synchrony is not simply accompanied with firing rate modulation and that the synchrony and the rate modulation might code similar information independently. We therefore conclude that the sub-millisecond firing synchrony in the hippocampus is an effective carrier for propagating information - as represented by the firing rate modulations - to downstream neurons.
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