Evidence map›Paper›PMID 19752745›Full record

ArticleJournal of immunotherapy (Hagerstown, Md. : 1997)2009

No correlation between clinical response to CTLA-4 blockade and presence of NY-ESO-1 antibody in patients with metastatic melanoma.

Stephanie L Goff, Paul F Robbins, Mona El-Gamil, Steven A Rosenberg

Abstract readLetterComment
In one paragraph

Article in Journal of immunotherapy (Hagerstown, Md. : 1997), 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Tumor regression in patients with metastatic synovial cell sarcoma and melanoma using genetically engineered lymphocytes reactive with NY-ESO-1.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2011
    Trial
  2. Article
  3. B cells and antibody production in melanoma.Mammalian genome : official journal of the International Mammalian Genome Society · 2018
    Review
  4. Article
  5. Review
  6. Review
  7. Review
  8. Review
  9. Review
  10. Review
  11. Article
  12. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Stephanie L Goff
Paul F Robbins
Mona El-Gamil
Steven A Rosenberg

Funding

Adoptive Cell Transfer Immunotherapy of CancerZIABC010984 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI ROSENBERG, STEVEN · 2009 to 2025
$56.8M
DNA Sequencing and FACS Core FacilitiesZICBC010948 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI ROBBINS, PAUL · 2009 to 2025
$35.6M
Adoptive Cell Transfer Immunotherapy of CancerZ01BC010984 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI ROSENBERG, STEVEN · 2008 to 2008
$1.5M
Intramural NIH HHS Z01 BC010984
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Antibody FormationAntibodies, BlockingAntibodies, MonoclonalAntigens, CDAntigens, NeoplasmClinical Trials as TopicCTLA-4 AntigenEnzyme-Linked Immunosorbent Assaygp100 Melanoma AntigenHumansImmunoglobulinsIpilimumabMelanomaMembrane GlycoproteinsMembrane ProteinsNeoplasm MetastasisAntibodies, BlockingAntibodies, MonoclonalAntigens, CDAntigens, NeoplasmCTAG1B protein, humanCTLA-4 AntigenCTLA4 protein, humangp100 Melanoma AntigenImmunoglobulinsIpilimumabMembrane GlycoproteinsMembrane ProteinsPeptide FragmentsPMEL protein, human

Identifiers

PMID19752745
PMCPMC6327840

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.