ArticleAnnals of family medicine
Yield of opportunistic targeted screening for type 2 diabetes in primary care: the diabscreen study.
Article in Annals of family medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 49 citations in OpenAlex.
- Cost and Health Care Utilization Implications of Bariatric Surgery Versus Intensive Lifestyle and Medical Intervention for Type 2 Diabetes.Obesity (Silver Spring, Md.) · 2017Trial
- Vascular outcomes in patients with screen-detected or clinically diagnosed type 2 diabetes: Diabscreen study follow-up.Annals of family medicineTrial
- Expanding Access to Early Diabetes Detection: A Pharmacy-Based Screening Pilot in Rural New South Wales.Health science reports · 2026Article
- Improving Diabetes and Pre-Diabetes Detection in the UK: Insights From HbA1c Screening in an Acute Hospital's Emergency Department.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2025Article
- Improving Diabetes Screening in the Primary Care Clinic.Joint Commission journal on quality and patient safety · 2023Article
- Middle-aged Health Checks Program Outputs in Non-communicable Diseases Screening in Iran.International journal of preventive medicine · 2019Article
- Understanding type 2 diabetes mellitus screening practices among primary care physicians: a qualitative chart-stimulated recall study.BMC family practice · 2017Article
- Feasibility of extracting data from electronic medical records for research: an international comparative study.BMC medical informatics and decision making · 2016Article
- The Need for Patient Follow-up Strategies to Confirm Diabetes Mellitus in Large Scale Opportunistic Screening.Journal of clinical and diagnostic research : JCDR · 2016Review
- Diabetes case finding in the emergency department, using HbA1c: an opportunity to improve diabetes detection, prevention, and care.BMJ open diabetes research & care · 2016Article
- Exploring the impact of chronic obstructive pulmonary disease (COPD) on diabetes control in diabetes patients: a prospective observational study in general practice.NPJ primary care respiratory medicine · 2015Observational
- Effect of mobile reminders on screening yield during opportunistic screening for type 2 diabetes mellitus in a primary health care setting: A randomized trial.Preventive medicine reports · 2015Article
- Observational
- Impact of bariatric surgery on health care utilization and costs among patients with diabetes.Medical care · 2012Article
- Prevalence of undiagnosed and suboptimally controlled diabetes by point-of-care HbA1C in unselected emergency department patients.Academic emergency medicine : official journal of the Society for Academic Emergency Medicine · 2011Article
- Article
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeIn screening for type 2 diabetes, guidelines recommend targeting high-risk individuals. Our objectives were to assess the yield of opportunistic targeted screening for type 2 diabetes in primary care and to assess the diagnostic value of various risk factors.
methodsIn 11 family practices (total practice population = 49,229) in The Netherlands, we conducted a stepwise opportunistic screening program among patients aged 45 to 75 years by (1) identifying high-risk individuals (=1 diabetes risk factor) and low-risk individuals using the electronic medical record, (2) obtaining a capillary fasting plasma glucose measurement, repeated on a separate day if the value was greater than 110 mg/dL, and (3) obtaining a venous sample if both capillary fasting plasma glucose values were greater than 110 mg/dL and at least 1 sample was 126 mg/dL or greater. We calculated the yield (percentage of invited patients with undiagnosed diabetes), number needed to screen (NNS), and diagnostic value of the risk factors (odds ratio and area under the receiver operating characteristic curve).
resultsWe invited for a first capillary measurement 3,724 high-risk patients seen during usual care and a random sample of 465 low-risk patients contacted by mail. The response rate was 90% and 86%, respectively. Ultimately, 101 high-risk patients (2.7%; 95% confidence interval [CI], 2.2%-3.3%; NNS = 37) and 2 low-risk patients (0.4%; 95% CI, 0.1%-1.6%; NNS = 233) had undiagnosed diabetes (P <.01). The prevalence of diabetes among patients 45 to 75 years old increased from 6.1% to 6.8% as a result. Among diagnostic models containing various risk factors, a model containing obesity alone was the best predictor of undiagnosed diabetes (odds ratio = 3.2; 95% CI, 2.0-5.2; area under the curve=0.63).
conclusionsThe yield of opportunistic targeted screening was fair; obesity alone was the best predictor of undiagnosed diabetes. Opportunistic screening for type 2 diabetes in primary care could target middle-aged and older adults with obesity.
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