Evidence map›Paper›PMID 19752045›Full record

ReviewBriefings in functional genomics & proteomics2009

Chromatin insulators: lessons from the fly.

B V Gurudatta, Victor G Corces

Abstract readReview
In one paragraph

Review in Briefings in functional genomics & proteomics, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed.

  1. Article
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  5. Article
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  7. Article
  8. Gene functioning and storage within a folded genome.Cellular & molecular biology letters · 2017
    Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

B V GurudattaDepartment of Biology, Emory University, 1510 Clifton Rd NE, Atlanta, GA 30322, USA.
Victor G Corces

Funding

MOLECULAR BASIS OF SUPPRESSION IN DROSOPHILAR01GM035463 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI CORCES, VICTOR G. · 1986 to 2020
$10.7M
NIGMS NIH HHS GM35463NIGMS NIH HHS R01 GM035463
6 · The paper itself

Abstract

Chromatin insulators are DNA-protein complexes with broad functions in nuclear biology. Drosophila has at least five different types of insulators; recent results suggest that these different insulators share some components that may allow them to function through common mechanisms. Data from genome-wide localization studies of insulator proteins indicate a possible functional specialization, with different insulators playing distinct roles in nuclear biology. Cells have developed mechanisms to control insulator activity by recruiting specialized proteins or by covalent modification of core components. Current results suggest that insulators set up cell-specific blueprints of nuclear organization that may contribute to the establishment of different patterns of gene expression during cell differentiation and development.

Indexed as

AnimalsBase SequenceChromatinDrosophila melanogasterDrosophila ProteinsInsulator ElementsChromatinDrosophila Proteins

Identifiers

PMID19752045
PMCPMC2742804

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.