ReviewExpert review of medical devices2009
New directions in nanofibrous scaffolds for soft tissue engineering and regeneration.
Review in Expert review of medical devices, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 113 citations in OpenAlex.
- Early Postoperative Conjunctival Complications Leading to Exposure of Surgically Implanted CorNeat EverPatch Devices.Ophthalmology · 2025Article
- In Vivo Cell Migration and Growth Within Electrospun Porous Nanofibrous Scaffolds with Different Pore Sizes in a Mouse Pouch Model.Journal of functional biomaterials · 2025Article
- Therapeutic Efficacy of an Erythromycin-Loaded Coaxial Nanofiber Coating in a Rat Model ofInternational journal of molecular sciences · 2024Article
- Evaluation of a biodegradable polyurethane patch for repair of diaphragmatic hernia in a rat model: A pilot study.Journal of pediatric surgery · 2023Article
- The Structure and Function of Next-Generation Gingival Graft Substitutes-A Perspective on Multilayer Electrospun Constructs with Consideration of Vascularization.International journal of molecular sciences · 2022Review
- Biomaterials and Meniscal Lesions: Current Concepts and Future Perspective.Pharmaceutics · 2021Review
- Tendon Tissue Repair in Prospective of Drug Delivery, Regenerative Medicines, and Innovative Bioscaffolds.Stem cells international · 2021Review
- Effective Reconstruction of Functional Urethra Promoted With ICG-001 Delivery Using Core-Shell Collagen/Poly(Llactide-co-caprolactone) [P(LLA-CL)] Nanoyarn-Based Scaffold: A Study in Dog Model.Frontiers in bioengineering and biotechnology · 2020Article
- Electrospun Fiber Mesh for High-Resolution Measurements of Oxygen Tension in Cranial Bone Defect Repair.ACS applied materials & interfaces · 2019Article
- Layer-by-layer nanofiber-enabled engineering of biomimetic periosteum for bone repair and reconstruction.Biomaterials · 2018Article
- Influence of shell compositions of solution blown PVP/PCL core-shell fibers on drug release and cell growth.RSC advances · 2018Article
- Strategic Design and Fabrication of Biomimetic 3D Scaffolds: Unique Architectures of Extracellular Matrices for Enhanced Adipogenesis and Soft Tissue Reconstruction.Scientific reports · 2018Article
- Influence of Nanofiber Orientation on Morphological and Mechanical Properties of Electrospun Chitosan Mats.Journal of healthcare engineering · 2018Article
- Multiscale technologies for treatment of ischemic cardiomyopathy.Nature nanotechnology · 2017Review
- Small Diameter Blood Vessels Bioengineered From Human Adipose-derived Stem Cells.Scientific reports · 2016Article
- [Progress and challenges in tissue engineering of intervertebral disc annulus fibrosus].Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2016Review
- Advancing biomaterials of human origin for tissue engineering.Progress in polymer science · 2016Article
- Application of Wnt Pathway Inhibitor Delivering Scaffold for Inhibiting Fibrosis in Urethra Strictures: In Vitro and in Vivo Study.International journal of molecular sciences · 2015Article
- Meniscus tissue engineering using a novel combination of electrospun scaffolds and human meniscus cells embedded within an extracellular matrix hydrogel.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2015Article
- Development and molecular characterization of polymeric micro-nanofibrous scaffold of a defined 3-D niche for in vitro chemosensitivity analysis against acute myeloid leukemia cells.International journal of nanomedicine · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
Abstract
This review focuses on the role of nanostructure and nanoscale materials for tissue engineering applications. We detail a scaffold production method (electrospinning) for the production of nanofiber-based scaffolds that can approximate many critical features of the normal cellular microenvironment, and so foster and direct tissue formation. Further, we describe new and emerging methods to increase the applicability of these scaffolds for in vitro and in vivo application. This discussion includes a focus on methods to further functionalize scaffolds to promote cell infiltration, methods to tune scaffold mechanics to meet in vivo demands and methods to control the release of pharmaceuticals and other biologic agents to modulate the wound environment and foster tissue regeneration. This review provides a perspective on the state-of-the-art production, application and functionalization of these unique nanofibrous structures, and outlines future directions in this growing field.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.