Evidence map›Paper›PMID 19750523›Full record

ReviewBirth defects research. Part C, Embryo today : reviews2009

Neural induction and factors that stabilize a neural fate.

Crystal D Rogers, Sally A Moody, Elena S Casey

Open access · greenAbstract readReview
In one paragraph

Review in Birth defects research. Part C, Embryo today : reviews, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 78 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Early Steps towards Hearing: Placodes and Sensory Development.International journal of molecular sciences · 2023
    Review
  6. Article
  7. Article
  8. Tissue Rotation of theJournal of developmental biology · 2022
    Article
  9. Article
  10. The Organizer and Its Signaling in Embryonic Development.Journal of developmental biology · 2021
    Review
  11. Article
  12. Review
  13. Review
  14. Article
  15. Article
  16. Specifying neural crest cells: From chromatin to morphogens and factors in between.Wiley interdisciplinary reviews. Developmental biology · 2018
    Review
  17. Article
  18. Tbx2 is required for the suppression of mesendoderm during early Xenopus development.Developmental dynamics : an official publication of the American Association of Anatomists · 2018
    Article
  19. Article
  20. The cellular and molecular basis of cnidarian neurogenesis.Wiley interdisciplinary reviews. Developmental biology · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Crystal D RogersDepartment of Biology, Georgetown University, Washington, District of Columbia, USA.
Sally A Moody
Elena S Casey
Georgetown University · USGeorge Washington University · US

Funding

NEURONAL LINEAGE DETERMINANTS IN EMBRYOSR01NS023158 · NINDS · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI MOODY, SALLY ANN · 1986 to 2006
$2.2M
Characterization of SoxB genes in neural developmentR01NS048918 · NINDS · GEORGETOWN UNIVERSITY · PI SILVA, ELENA M · 2005 to 2008
$1.1M
NINDS NIH HHS NS0489180NINDS NIH HHS NS23158NINDS NIH HHS R01 NS023158NINDS NIH HHS R01 NS048918
6 · The paper itself

Abstract

The neural ectoderm of vertebrates forms when the bone morphogenetic protein (BMP) signaling pathway is suppressed. Herein, we review the molecules that directly antagonize extracellular BMP and the signaling pathways that further contribute to reduce BMP activity in the neural ectoderm. Downstream of neural induction, a large number of "neural fate stabilizing" (NFS) transcription factors are expressed in the presumptive neural ectoderm, developing neural tube and ultimately in neural stem cells. Herein, we review what is known about their activities during normal development to maintain a neural fate and regulate neural differentiation. Further elucidation of how the NFS genes interact to regulate neural specification and differentiation should ultimately prove useful for regulating the expansion and differentiation of neural stem and progenitor cells.

Indexed as

Cell DifferentiationGene Expression Regulation, DevelopmentalSignal TransductionAnimalsBone Morphogenetic ProteinsEctodermNeuronsStem CellsTranscription FactorsXenopus laevisXenopus ProteinsBone Morphogenetic ProteinsTranscription FactorsXenopus Proteins

Identifiers

PMID19750523
PMCPMC2756055
OpenAlexW2036895854

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.