ReviewInternational journal of chronic obstructive pulmonary disease2009
Targeted treatment in COPD: a multi-system approach for a multi-system disease.
Review in International journal of chronic obstructive pulmonary disease, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 24 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Prospective Baseline Assessment of the Risk of Osteoporosis in Patients With Chronic Obstructive Lung Disease and Outcomes After 2 Years; a Pilot Study
Impact of a Hospital Physical Therapy Program on Exacerbated Chronic Obstructive Pulmonary Disease Patients: A Randomized Controlled Trial
Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 68 citations in OpenAlex.
- [Spanish COPD Guidelines (GesEPOC): Pharmacological treatment of stable COPD].Atencion primaria · 2012Guideline
- Predicting treatable traits for long-acting bronchodilators in patients with stable COPD.International journal of chronic obstructive pulmonary disease · 2017Trial
- Chemical exposure and alveolar macrophages responses: 'the role of pulmonary defense mechanism in inhalation injuries'.BMJ open respiratory research · 2023Review
- Omega-3 Polyunsaturated Fatty Acids in Managing Comorbid Mood Disorders in Chronic Obstructive Pulmonary Disease (COPD): A Review.Journal of clinical medicine · 2023Review
- Therapeutic Potential of Small Molecules Targeting Oxidative Stress in the Treatment of Chronic Obstructive Pulmonary Disease (COPD): A Comprehensive Review.Molecules (Basel, Switzerland) · 2022Review
- Ventilator-induced lung injury results in oxidative stress response and mitochondrial swelling in a mouse model.Laboratory animal research · 2022Article
- Construction of a Suite of Computable Biological Network Models Focused on Mucociliary Clearance in the Respiratory Tract.Frontiers in genetics · 2019Article
- Exacerbations and healthcare resource utilization among COPD patients in a Swedish registry-based nation-wide study.BMC pulmonary medicine · 2018Article
- Relationship between obstructive lung disease and non-alcoholic fatty liver disease in the Korean population: Korea National Health and Nutrition Examination Survey, 2007-2010.International journal of chronic obstructive pulmonary disease · 2018Article
- Oxidant status, iron homeostasis, and carotenoid levels of COPD patients with advanced disease and LTOT.European clinical respiratory journal · 2018Article
- Sauna bathing reduces the risk of respiratory diseases: a long-term prospective cohort study.European journal of epidemiology · 2017Article
- Recognition, diagnosis, and treatment of cognitive and psychiatric disorders in patients with COPD.International journal of chronic obstructive pulmonary disease · 2017Review
- Article
- Redox-Dependent Calpain Signaling in Airway and Pulmonary Vascular Remodeling in COPD.Advances in experimental medicine and biology · 2017Article
- Asthma and chronic obstructive pulmonary disease overlap: asthmatic chronic obstructive pulmonary disease or chronic obstructive asthma?Therapeutic advances in respiratory disease · 2016Review
- N-acetylcysteine in COPD: why, how, and when?Multidisciplinary respiratory medicine · 2015Review
- Efficacy of bronchoscopic lung volume reduction by endobronchial valves in patients with heterogeneous emphysema: report on the first Asian cases.Journal of Korean medical science · 2014Article
- Defining phenotypes in COPD: an aid to personalized healthcare.Molecular diagnosis & therapy · 2014Review
- [Alveolar epithelial cell injury as an etiopathogenic factor in pulmonary fibrosis].Archivos de bronconeumologia · 2012Review
- The overlap phenotype: the (missing) link between asthma and COPD.Multidisciplinary respiratory medicine · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chronic obstructive pulmonary disease is a varied condition when examined from a number of different perspectives including factors which influence disease development, pathological process and clinical features. There may be a complex interaction between the degree by which each of these processes influences the development of COPD and the subsequent clinical phenotype with which the patient presents. The varied host response and subsequent clinical phenotype has generated much interest in recent years. It is possible that failure of treatment to impact on mortality and reverse the disease process is because of the heterogeneous nature of the condition. Identification and targeted treatment of clinical and pathological phenotypes within the broad spectrum of COPD may therefore improve outcome. This article will review previous work which has attempted to phenotype COPD and identify if specific treatment for these phenotypes has been shown to be of benefit. It will examine the work on pathological processes and clinical manifestations, both pulmonary and systemic, and will focus on pharmacological therapies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.