Interferon-alfa, interferon-lambda and hepatitis C.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it.

1. An update on the management of hepatitis C: consensus guidelines from the Canadian Association for the Study of the Liver.Canadian journal of gastroenterology = Journal canadien de gastroenterologie · 2012
   Guideline
2. Baseline levels of soluble CD14 and CD16+56- natural killer cells are negatively associated with response to interferon/ribavirin therapy during HCV-HIV-1 coinfection.The Journal of infectious diseases · 2012
   Trial
3. Evolutionary genetic dissection of human interferons.The Journal of experimental medicine · 2011
   Trial
4. Coffee consumption is associated with response to peginterferon and ribavirin therapy in patients with chronic hepatitis C.Gastroenterology · 2011
   Trial
5. Association of IL28B gene variations with mathematical modeling of viral kinetics in chronic hepatitis C patients with IFN plus ribavirin therapy.Proceedings of the National Academy of Sciences of the United States of America · 2011
   Trial
6. An IL28B genotype-based clinical prediction model for treatment of chronic hepatitis C.PloS one · 2011
   Trial
7. Fibrosis and Hepatocarcinogenesis: Role of Gene-Environment Interactions in Liver Disease Progression.International journal of molecular sciences · 2024
   Review
8. Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research · 2023
   Article
9. Model-based cell clustering and population tracking for time-series flow cytometry data.BMC bioinformatics · 2019
   Article
10. Meeting Overview: Interferon Lambda-Disease Impact and Therapeutic Potential.Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research · 2019
    Article
11. Immune checkpoint blockade and interferon-α in melanoma.Seminars in oncology · 2015
    Review
12. Effect of Interleukin-29 on Interferon-α Secretion by Peripheral Blood Mononuclear Cells.Cell journal · 2015
    Article
13. Incidence and cost of treatment-emergent comorbid events in insured patients with chronic hepatitis C virus infection: a retrospective cohort study.BMC health services research · 2014
    Article
14. Natural cytotoxicity receptor-dependent natural killer cytolytic activity directed at hepatitis C Virus (HCV) is associated with liver inflammation, African American race, IL28B genotype, and response to pegylated interferon/ribavirin therapy in chronic HCV infection.The Journal of infectious diseases · 2014
    Article
15. Ex vivo induction of IFN-λ3 by a TLR7 agonist determines response to Peg-IFN/ribavirin therapy in chronic hepatitis C patients.Journal of gastroenterology · 2014
    Article
16. Role of viral and host factors in interferon based therapy of hepatitis C virus infection.Virology journal · 2013
    Review
17. Novel therapies for hepatitis C - one pill fits all?Nature reviews. Drug discovery · 2013
    Review
18. MicroRNA-27a regulates lipid metabolism and inhibits hepatitis C virus replication in human hepatoma cells.Journal of virology · 2013
    Article
19. Association of IL28B genotypes with metabolic profiles and viral clearance rate in chronic hepatitis C patients.Hepatology international · 2013
    Article
20. Viral hepatitis C gets personal--the value of human genomics to public health.Public health genomics · 2013
    Review

Corrections and comments

• Comment on
  Genome-wide association of IL28B with response to pegylated interferon-alpha and ribavirin therapy for chronic hepatitis C.2009
• Comment on
  IL28B is associated with response to chronic hepatitis C interferon-alpha and ribavirin therapy.2009

Authors and funding

1 author.

Funding

Abstract

PubMed holds no abstract for this paper.

Indexed as