Evidence map›Paper›PMID 19749043›Full record

ArticleJournal of bacteriology2009

YjhS (NanS) is required for Escherichia coli to grow on 9-O-acetylated N-acetylneuraminic acid.

Susan M Steenbergen, Jamie L Jirik, Eric R Vimr

Abstract read
In one paragraph

Article in Journal of bacteriology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Article
  2. Article
  3. Response ofMarine life science & technology · 2023
    Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. The sialateThe Journal of biological chemistry · 2017
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Susan M SteenbergenLaboratory of Sialobiology, Department of Pathobiology, University of Illinois at Urbana-Champaign, Urbana, Illinois 61802, USA.
Jamie L Jirik
Eric R Vimr

Funding

Regulation of the Poly Sialic Virulence FactorR01AI042015 · NIAID · UNIVERSITY OF ILLINOIS URBANA-CHAMPAIGN · PI VIMR, ERIC ROSS · 1998 to 2014
$2.6M
Regulation of the Poly Sialic Virulence FactorR56AI042015 · NIAID · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI VIMR, ERIC ROSS · 2009 to 2009
$238k
NIAID NIH HHS AI042015NIAID NIH HHS R01 AI042015NIAID NIH HHS R56 AI042015
6 · The paper itself

Abstract

The nanATEK-yhcH, yjhATS, and yjhBC operons in Escherichia coli are coregulated by environmental N-acetylneuraminic acid, the most prevalent sialic acid in nature. Here we show that YjhS (NanS) is a probable 9-O-acetyl N-acetylneuraminic acid esterase required for E. coli to grow on this alternative sialic acid, which is commonly found in mammalian host mucosal sites.

Indexed as

Escherichia coliEscherichia coli ProteinsGene Expression Regulation, BacterialN-Acetylneuraminic AcidSialic Acids9-O-acetyl-N-acetylneuraminic acidEscherichia coli ProteinsN-Acetylneuraminic AcidSialic Acids

Identifiers

PMID19749043
PMCPMC2772488

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.