ArticleMedical hypotheses2010
Similarities in features of autism and asthma and a possible link to acetaminophen use.
Article in Medical hypotheses, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it, 68 citations in OpenAlex.
- Pooled it
- Beyond the Headlines: Examining the Evidence Around Acetaminophen and Autism Risk.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2026Article
- Postnatal acetaminophen exposure and neurodevelopmental outcomes at 18-21 months corrected gestational age in preterm infants <29 weeks gestation: a retrospective cohort study.Pediatric research · 2024Article
- Endocannabinoid System Dysregulation from Acetaminophen Use May Lead to Autism Spectrum Disorder: Could Cannabinoid Treatment Be Efficacious?Molecules (Basel, Switzerland) · 2021Review
- Intrauterine Exposure to Acetaminophen and Adverse Developmental Outcomes: Epidemiological Findings and Methodological Issues.Current environmental health reports · 2021Review
- Associations of prenatal or infant exposure to acetaminophen or ibuprofen with mid-childhood executive function and behaviour.Paediatric and perinatal epidemiology · 2020Article
- Associations of acetaminophen use during pregnancy and the first year of life with neurodevelopment in early childhood.Paediatric and perinatal epidemiology · 2020Article
- Postnatal Acetaminophen and Potential Risk of Autism Spectrum Disorder among Males.Behavioral sciences (Basel, Switzerland) · 2020Article
- Chronic Pain Prevalence and Exposures during Pregnancy.Pain research & management · 2019Article
- Chronic pain during pregnancy: a review of the literature.International journal of women's health · 2018Review
- Endocannabinod Signal Dysregulation in Autism Spectrum Disorders: A Correlation Link between Inflammatory State and Neuro-Immune Alterations.International journal of molecular sciences · 2017Review
- The role of oxidative stress, inflammation and acetaminophen exposure from birth to early childhood in the induction of autism.The Journal of international medical research · 2017Review
- Developmental neurotoxicity of inhaled ambient ultrafine particle air pollution: Parallels with neuropathological and behavioral features of autism and other neurodevelopmental disorders.Neurotoxicology · 2017Review
- Environmental factors influencing the risk of autism.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2017Review
- Acetaminophen Use for Fever in Children Associated with Autism Spectrum Disorder.Autism-open access · 2016Article
- Ritual circumcision and risk of autism spectrum disorder in 0- to 9-year-old boys: national cohort study in Denmark.Journal of the Royal Society of Medicine · 2015Article
- Glyphosate, pathways to modern diseases III: Manganese, neurological diseases, and associated pathologies.Surgical neurology international · 2015Article
- A model for the induction of autism in the ecosystem of the human body: the anatomy of a modern pandemic?Microbial ecology in health and disease · 2015Article
- Organic Compounds Detected in Deciduous Teeth: A Replication Study from Children with Autism in Two Samples.Journal of environmental and public health · 2015Article
- Co-occurrence of autism and asthma in a nationally-representative sample of children in the United States.Journal of autism and developmental disorders · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
Autism and autism spectrum disorders are enigmatic conditions that have their origins in the interaction of genes and environmental factors. In this hypothesis, genes statistically associated with autism are emphasized to be important in inflammation and in innate immune pathways, including pathways for susceptibility to asthma. The role of acetaminophen (paracetamol) in an increased risk for asthma is described and a possible similar link to an increased risk for autism is suggested.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.