ReviewAntioxidants & redox signaling2010
Threading the needle: getting selenocysteine into proteins.
Review in Antioxidants & redox signaling, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed.
- Nutritional supplementation remodels yak cardiac molecular networks through selenoprotein activation and immune quiescence.Frontiers in nutrition · 2026Article
- Replacing of Cysteine with Selenocysteine: Biochemical Considerations, Computational Modeling, and Protein Engineering Applications.Methods in molecular biology (Clifton, N.J.) · 2026Article
- A novel microtubule inhibitor promotes tumor ferroptosis by attenuating SLC7A11/GPX4 signaling.Cell death discovery · 2023Article
- Dynamics of ribosome composition and ribosomal protein phosphorylation in immune signaling in Arabidopsis thaliana.Nucleic acids research · 2023Article
- Selenium Effects on Oxidative Stress-Induced Calcium Signaling Pathways in Parkinson's Disease.Indian journal of clinical biochemistry : IJCB · 2022Review
- Chemoproteomic interrogation of selenocysteine by low-pH isoTOP-ABPP.Methods in enzymology · 2022Article
- Expression of selenoproteins via genetic code expansion in mammalian cells.Methods in enzymology · 2022Article
- SECISBP2 is a novel prognostic predictor that regulates selenoproteins in diffuse large B-cell lymphoma.Laboratory investigation; a journal of technical methods and pathology · 2021Article
- One-pot organocatalytic/multicomponent approach for the preparation of novel enantioenriched non-natural selenium-based peptoids and peptide-peptoid conjugates.Molecular diversity · 2020Article
- Comparative genomic analysis of selenium utilization traits in different marine environments.Journal of microbiology (Seoul, Korea) · 2020Article
- Chemical Biology Approaches to Interrogate the Selenoproteome.Accounts of chemical research · 2019Review
- Selenium, Selenoproteins and Viral Infection.Nutrients · 2019Review
- Cell-Type Specific Analysis of Selenium-Related Genes in Brain.Antioxidants (Basel, Switzerland) · 2019Article
- Global importance of RNA secondary structures in protein-coding sequences.Bioinformatics (Oxford, England) · 2019Article
- Review
- A Quantitative Chemoproteomic Platform to Monitor Selenocysteine Reactivity within a Complex Proteome.Cell chemical biology · 2018Article
- Selenoprotein S: a therapeutic target for diabetes and macroangiopathy?Cardiovascular diabetology · 2017Review
- Subtractional Heterogeneity: A Crucial Step toward Defining Specialized Ribosomes.Molecular cell · 2017Article
- Ferroptosis: Death by Lipid Peroxidation.Trends in cell biology · 2016Review
- SELENOPROTEINS. CRL2 aids elimination of truncated selenoproteins produced by failed UGA/Sec decoding.Science (New York, N.Y.) · 2015Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
The co-translational incorporation of selenocysteine (Sec) requires that UGA be recognized as a sense rather than a nonsense codon. This is accomplished by the concerted action of a Sec insertion sequence (SECIS) element, SECIS binding protein 2, and a ternary complex of the Sec specific elongation factor, Sec-tRNA(Sec), and GTP. The mechanism by which they alter the canonical protein synthesis reaction has been elusive. Here we present an overview of the mechanistic perspective on Sec incorporation, highlighting recent advances in the field.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.