ArticleThe Canadian journal of cardiology2009
Functional health status of adolescents after the Fontan procedure -- comparison with their siblings.
Article in The Canadian journal of cardiology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.
- Health-Related Quality of Life in Children, Adolescents, and Adults With a Fontan Circulation: A Meta-Analysis.Journal of the American Heart Association · 2020Pooled it
- Effect of Sildenafil on Pressure-Volume Loop Measures of Ventricular Function in Fontan Patients.Pediatric cardiology · 2016Trial
- Exercise Capacity, Endothelial Function, Muscle Mass, and Strength in Pediatric Patients With Fontan Circulation.CJC pediatric and congenital heart disease · 2026Article
- School Performance and Learning Challenges in Children and Adolescents with Congenital Heart Disease.Pediatric cardiology · 2026Review
- Design and rationale of re-energize fontan: Randomized exercise intervention designed to maximize fitness in fontan patients.American heart journal · 2023Article
- Home-Based Long-Term Physical Endurance and Inspiratory Muscle Training for Children and Adults With Fontan Circulation-Initial Results From a Prospective Study.Frontiers in cardiovascular medicine · 2021Article
- Emotional quality-of-life and patient-reported limitation in sports participation in children with uncorrected congenital and acquired heart disease in healthcare-restricted settings in low- and middle-income countries.Cardiology in the young · 2020Article
- Measurement framework for the Environmental influences on Child Health Outcomes research program.Current opinion in pediatrics · 2018Review
- Health-related quality of life in congenital heart disease surgery patients in Pakistan: protocol for a mixed-methods study.BMJ open · 2017Article
- Assessment of Quality of Life in Young Patients with Single Ventricle after the Fontan Operation.The Journal of pediatrics · 2016Observational
- Health-Related Quality of Life in Children and Adolescents with Hereditary Bleeding Disorders and in Children and Adolescents with Stroke: Cross-Sectional Comparison to Siblings and Peers.BioMed research international · 2016Article
- High Overweight and Obesity in Fontan Patients: A 20-Year History.Pediatric cardiology · 2016Article
- Functional health status in children and adolescents after Fontan: comparison of generic and disease-specific assessments.Cardiology in the young · 2014Observational
- Patient-reported quality of life outcomes for children with serious congenital heart defects.Archives of disease in childhood · 2014Article
- The relationship of patient medical and laboratory characteristics to changes in functional health status in children and adolescents after the Fontan procedure.Pediatric cardiology · 2014Article
- Health related quality of life of children with rheumatic heart diseases: reliability of the Brazilian version of the Pediatric Quality of Life Inventory™ Cardiac Module scale.Health and quality of life outcomes · 2013Article
- Neurodevelopment and quality of life for children with hypoplastic left heart syndrome: current knowns and unknowns.Cardiology in the young · 2011Review
- Comparison of echocardiographic and pressure-volume loop indices of systolic function in patients with single ventricle physiology: a preliminary report.Congenital heart diseaseArticle
- Clinical profile of the adolescent/adult Fontan survivor.Congenital heart diseaseArticle
- Quality of life, health status, and depression: comparison between adolescents and adults after the Fontan procedure with healthy counterparts.The Journal of cardiovascular nursingArticle
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundStudies have suggested that patients who have undergone the Fontan procedure experience lower functional health status and diminished exercise capacity compared with other children.
objectivesTo compare the functional health status of Fontan patients with and without siblings, assess whether there are any differences between Fontan patients and their siblings, and determine associated factors.
methodsA cross-sectional, single-centre, observational study was performed on Fontan patients 10 to 20 years of age, and their sibling closest in age, followed in a tertiary pediatric hospital. Functional health status was measured by the Child Health Questionnaire Child Form and the Pediatric Quality of Life Inventory.
resultsA total of 68 patients and 38 siblings were enrolled. Patients with siblings scored significantly lower on numerous domains of physical functional status than those without siblings. Compared with their matched siblings, Fontan patients reported significantly lower scores in all domains of the Pediatric Quality of Life Inventory and on physical (but not psychosocial) domains of the Child Health Questionnaire Child Form. Factors associated with increased patient-sibling differences included younger patient age, female sex, intracardiac lateral tunnel Fontan connection and lower ejection fraction at the time of study enrollment.
conclusionsAdolescents with Fontan physiology reported a lower functional health status in physical domains than their siblings, but had similar status in psychosocial domains. Having a sibling was associated with lower reported functional health status, suggesting an important effect of self-perceived physical limitations over true limitations.
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Registered trials
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