Evidence map›Paper›PMID 19743810›Full record

ArticleJournal of natural products2009

Isolation and structural elucidation of euryjanicins B-D, proline-containing cycloheptapeptides from the Caribbean marine sponge Prosuberites laughlini.

Brunilda Vera, Jan Vicente, Abimael D Rodríguez

Abstract read
In one paragraph

Article in Journal of natural products, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Controversy of Peptide Cyclization from Tripeptide.Molecules (Basel, Switzerland) · 2021
    Article
  3. Review
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Brunilda VeraDepartment of Chemistry, University of Puerto Rico, U. P. R. Station, San Juan, PR 00931-3346.
Jan Vicente
Abimael D Rodríguez

Funding

X-RAY STUDY OF SYNTHETIC OXYGEN CARRIERS RELATED TO BIOLOGICAL SYSTEMSS06GM008102 · NIGMS · UNIVERSITY OF PUERTO RICO RIO PIEDRAS · PI ARCE, RAFAEL · 1989 to 2008
$23.8M
RIO PIEDRAS MARC U*STAR DEVELOPMENT PROGRAMT34GM007821 · NIGMS · UNIVERSITY OF PUERTO RICO RIO PIEDRAS · PI CARBALLEIRA, NESTOR MANUEL · 1985 to 2020
$20.3M
New Leads Against Cancer and Infectious Diseases from Puerto Rican Reef SpeciesSC1GM086271 · NIGMS · UNIVERSITY OF PUERTO RICO RIO PIEDRAS · PI RODRIGUEZ, ABIMAEL D · 2010 to 2013
$1.2M
NIGMS NIH HHS S06 GM008102NIGMS NIH HHS S06 GM 08102NIGMS NIH HHS SC1 GM086271NIGMS NIH HHS T34 GM007821
6 · The paper itself

Abstract

Three new cyclic peptides, euryjanicins B (2), C (3), and D (4), have been isolated from the Puerto Rican marine sponge Prosuberites laughlini, and the structures were elucidated by chemical degradation, ESIMS/MS, and extensive 2D NMR methods. When tested against the National Cancer Institute 60 tumor cell line panel, all of the purified isolates displayed weak cytotoxicity.

Indexed as

AnimalsAntineoplastic AgentsCaribbean RegionDrug Screening Assays, AntitumorHumansMarine BiologyMolecular StructureNuclear Magnetic Resonance, BiomolecularPeptides, CyclicPoriferaProlineAntineoplastic Agentseuryjanicin Beuryjanicin Ceuryjanicin DPeptides, CyclicProline

Identifiers

PMID19743810
PMCPMC5328627

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.