ReviewNature2009
Chromosome crosstalk in three dimensions.
Review in Nature, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 79 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
79 citing papers in PubMed.
- Challenges in Analyzing Functional Epigenetic Data in Perspective of Adolescent Psychiatric Health.International journal of molecular sciences · 2022Review
- Predict long-range enhancer regulation based on protein-protein interactions between transcription factors.Nucleic acids research · 2021Article
- Article
- Modeling and analysis of Hi-C data by HiSIF identifies characteristic promoter-distal loops.Genome medicine · 2020Article
- Aneuploidy and gene expression: is there dosage compensation?Epigenomics · 2019Review
- Male-Specific Long Noncoding RNAInternational journal of molecular sciences · 2019Article
- Understanding the 3D genome: Emerging impacts on human disease.Seminars in cell & developmental biology · 2019Review
- Three-dimensional analysis reveals altered chromatin interaction by enhancer inhibitors harbors TCF7L2-regulated cancer gene signature.Journal of cellular biochemistry · 2019Article
- An AR-ERG transcriptional signature defined by long-range chromatin interactomes in prostate cancer cells.Genome research · 2019Article
- Article
- Spatial organization of chromosome territories in the interphase nucleus of trisomy 21 cells.Chromosoma · 2018Article
- The transcriptional regulator CCCTC-binding factor limits oxidative stress in endothelial cells.The Journal of biological chemistry · 2018Article
- Enhancer functions in three dimensions: beyond the flat world perspective.F1000Research · 2018Review
- Effect of Interaction between Chromatin Loops on Cell-to-Cell Variability in Gene Expression.PLoS computational biology · 2016Article
- In silico transcriptional regulation and functional analysis of dengue shock syndrome associated SNPs in PLCE1 and MICB genes.Functional & integrative genomics · 2016Article
- Three-Color Chromosome Painting as Seen through the Eyes of mFISH: Another Look at Radiation-Induced Exchanges and Their Conversion to Whole-Genome Equivalency.Frontiers in oncology · 2016Article
- 3CPET: finding co-factor complexes from ChIA-PET data using a hierarchical Dirichlet process.Genome biology · 2015Article
- Mango: a bias-correcting ChIA-PET analysis pipeline.Bioinformatics (Oxford, England) · 2015Article
- A possible role of Drosophila CTCF in mitotic bookmarking and maintaining chromatin domains during the cell cycle.Biological research · 2015Article
- Orbital dermatofibrosarcoma protuberans with intracranial extension preceded by recurrent leiomyoma of the orbit: a case report.Journal of medical case reports · 2015Article
19 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The genome forms extensive and dynamic physical interactions with itself in the form of chromosome loops and bridges, thus exploring the three-dimensional space of the nucleus. It is now possible to examine these interactions at the molecular level, and we have gained glimpses of their functional implications. Chromosomal interactions can contribute to the silencing and activation of genes within the three-dimensional context of the nuclear architecture. Technical advances in detecting these interactions contribute to our understanding of the functional organization of the genome, as well as its adaptive plasticity in response to environmental changes during development and disease.
Indexed as
Identifiers
19741702What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.