ArticleJournal of clinical microbiology2009
Molecular characteristics of German G8P[4] rotavirus strain GER1H-09 suggest that a genotyping and subclassification update is required for G8.
Article in Journal of clinical microbiology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Genetic diversity of circulating rotavirus strains in Tanzania prior to the introduction of vaccination.PloS one · 2014Trial
- The Evolution of Post-Vaccine G8P[4] Group a Rotavirus Strains in Rwanda; Notable Variance at the Neutralization Epitope Sites.Pathogens (Basel, Switzerland) · 2023Article
- Article
- Genotype distribution and evolutionary analysis of rotavirus associated with acute diarrhea outpatients in Hubei, China, 2013-2016.Virologica Sinica · 2022Article
- Genomic constellation of human Rotavirus A strains identified in Northern Brazil: a 6-year follow-up (2010-2016).Revista do Instituto de Medicina Tropical de Sao Paulo · 2020Article
- Article
- Putative vaccine breakthrough event associated with heterotypic rotavirus infection in newborn calves, Turkey, 2015.Veterinary microbiology · 2017Article
- Rotavirus Strain Trends During the Postlicensure Vaccine Era: United States, 2008-2013.The Journal of infectious diseases · 2016Article
- Rotavirus genotypes in sewage treatment plants and in children hospitalized with acute diarrhea in Italy in 2010 and 2011.Applied and environmental microbiology · 2015Article
- Review of global rotavirus strain prevalence data from six years post vaccine licensure surveillance: is there evidence of strain selection from vaccine pressure?Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2014Review
- Genetic diversity of porcine group A rotavirus strains in the UK.Veterinary microbiology · 2014Article
- Molecular epidemiology of contemporary G2P[4] human rotaviruses cocirculating in a single U.S. community: footprints of a globally transitioning genotype.Journal of virology · 2014Article
- G8 rotaviruses with conserved genotype constellations detected in Malawi over 10 years (1997-2007) display frequent gene reassortment among strains co-circulating in humans.The Journal of general virology · 2013Article
- Full-genome characterization of a G8P[8] rotavirus that emerged among children with diarrhea in Croatia in 2006.Journal of clinical microbiology · 2013Article
- First reports of human rotavirus G8P[4] gastroenteritis in the United States.Journal of clinical microbiology · 2012Article
- Uniformity of rotavirus strain nomenclature proposed by the Rotavirus Classification Working Group (RCWG).Archives of virology · 2011Article
- Diversity of group A rotavirus genes detected in the Triângulo Mineiro region, Minas Gerais, Brazil.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]Article
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A rare G8P[4] rotavirus, designated GER1H-09, was detected in a stool sample from an infant suffering from repeated episodes of emesis for 2 days without diarrhea. Sequencing of all genomic RNA segments was performed, and complete coding sequences were determined. The VP7 amino acid sequence revealed a close phylogenetic relationship to human G8P[6] and G8P[8] isolates from Slovenia and Africa. GER1H-09 shared typical amino acid residues within variable regions VR3 to VR7 with those strains, and their subclassification as lineage G8-II rotaviruses is proposed. The variability in VR3 was identified as the likely reason for the failure in genotyping G8-II rotaviruses by commonly used multiplex PCR. Furthermore, the sequences of associated structural and nonstructural proteins showed high amino acid identities to DS-1-like rotaviruses. The genotype composition of GER1H-09 (G8-P[4]-I2-R2-C2-M2-A2-N2-T2-E2-H2) suggests the occurrence of reassortment events between G8 genotypes and human DS-1-like G2P[4] rotaviruses.
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