Trial reportAmerican journal of epidemiology2009
Biomarker validation of reports of recent sexual activity: results of a randomized controlled study in Zimbabwe.
Trial report in American journal of epidemiology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 92 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
92 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Comparison of the ACASI Mode to Other Survey Modes in Sexual Behavior Surveys in Asia and Sub-Saharan Africa: Systematic Literature Review.Journal of medical Internet research · 2022Pooled it
- Systematic assessment of condom use measurement in evaluation of HIV prevention interventions: need for standardization of measures.AIDS and behavior · 2014Pooled it
- Interviewing adolescent girls about sexual and reproductive health: a qualitative study exploring how best to ask questions in structured follow-up interviews in a randomized controlled trial in Zambia.Reproductive health · 2022Trial
- Effectiveness of erectogenic condom against semen exposure among women in Vietnam: Randomized controlled trial.PloS one · 2022Trial
- Punto Seguro: A Randomized Controlled Pilot Using Conditional Economic Incentives to Reduce Sexually Transmitted Infection Risks in Mexico.AIDS and behavior · 2017Trial
- Assessment of the vaginal residence time of biomarkers of semen exposure.Contraception · 2016Trial
- Divergent adherence estimates with pharmacokinetic and behavioural measures in the MTN-003 (VOICE) study.Journal of the International AIDS Society · 2016Trial
- Y chromosome and HIV DNA detection in vaginal swabs as biomarkers of semen and HIV exposure in women.Sexually transmitted diseases · 2014Trial
- Using biomarkers to assess the validity of sexual behavior reporting across interview modes among young women in Kampala, Uganda.Studies in family planning · 2014Trial
- An evaluation of methods to improve the reporting of adherence in a placebo gel trial in Andhra Pradesh, India.AIDS and behavior · 2013Trial
- Adherence and acceptability in MTN 001: a randomized cross-over trial of daily oral and topical tenofovir for HIV prevention in women.AIDS and behavior · 2013Trial
- Randomized controlled trial on the effectiveness of counseling messages for avoiding unprotected sexual intercourse during sexually transmitted infection and reproductive tract infection treatment among female sexually transmitted infection clinic patients.Sexually transmitted diseases · 2013Trial
- Trial
- Adverse adolescent reproductive health outcomes after pelvic inflammatory disease.Archives of pediatrics & adolescent medicine · 2011Trial
- Change in condom and other barrier method use during and after an HIV prevention trial in Zimbabwe.Journal of the International AIDS Society · 2010Trial
- Association Between Negative Pregnancy Desires and Recent Condomless Sex Among Couples in Vietnam.Journal of sex research · 2026Article
- Quantifying population-level sexual risk behavior through HSV-2 transmission dynamics in the United States, 1950-2020.Scientific reports · 2025Article
- A PrEP Demonstration Project Using eHealth and Community Outreach to Justice-Involved Cisgender Women and Their Risk Networks.AIDS and behavior · 2022Article
- Predicting the Risk of Human Immunodeficiency Virus Type 1 (HIV-1) Acquisition in Rural South Africa Using Geospatial Data.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2022Article
- The Value of Assessing Self-Reported and Biological Indicators of Outcomes in Evaluating HIV Programs.Current HIV/AIDS reports · 2021Review
32 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Challenges in the accurate measurement of sexual behavior in human immunodeficiency virus (HIV) prevention research are well documented and have prompted discussion about whether valid assessments are possible. Audio computer-assisted self-interviewing (ACASI) may increase the validity of self-reported behavioral data. In 2006-2007, Zimbabwean women participated in a randomized, cross-sectional study that compared self-reports of recent vaginal sex and condom use collected through ACASI or face-to-face interviewing (FTFI) with a validated objective biomarker of recent semen exposure (prostate-specific antigen (PSA) levels). Of 910 study participants, 196 (21.5%) tested positive for PSA, an indication of semen exposure during the previous 2 days. Of these 196 participants, 23 (11.7%) reported no sex in the previous 2 days, with no difference in reported sexual activity between interview modes (12.5% ACASI vs. 10.9% FTFI; Fisher's exact test: P = 0.72). In addition, 71 PSA-positive participants (36.2%) reported condom-protected vaginal sex only; their reports also indicated no difference between interview modes (33.7% ACASI vs. 39.1% FTFI; P = 0.26). Only 52% of PSA-positive participants reported unprotected sex during the previous 2 days. Self-report was a poor predictor of recent sexual activity and condom use in this study, regardless of interview mode, providing evidence that such data should be interpreted cautiously.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.