ArticleDiagnostic pathology2009
Genotype distribution of cervical human papillomavirus DNA in women with cervical lesions in Bioko, Equatorial Guinea.
Article in Diagnostic pathology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 27 citations in OpenAlex.
- Pooled it
- Association between cyclin D1 G870A polymorphism and cervical cancer risk: a cumulative meta-analysis involving 2,864 patients and 3,898 controls.Diagnostic pathology · 2014Pooled it
- Human Papillomavirus Coinfection in the Cervical Intraepithelial Lesions and Cancer of Mexican Patients.BioMed research international · 2020Article
- Human papillomavirus (HPV) genotype distribution in penile carcinoma: Association with clinic pathological factors.PloS one · 2018Article
- High prevalence of co-infection between human papillomavirus (HPV) 51 and 52 in Mexican population.BMC cancer · 2017Article
- Human papillomavirus genotypes distribution among Gabonese women with normal cytology and cervical abnormalities.Infectious agents and cancer · 2016Article
- Prevalence of human papilloma virus (HPV) and its genotypes in cervical specimens of Egyptian women by linear array HPV genotyping test.Infectious agents and cancer · 2016Article
- Human papillomavirus related cervical cancer and anticipated vaccination challenges in Ethiopia.International journal of health sciences · 2016Review
- Human papillomavirus genotypes distribution in cervical cancer cases in Gabon.Infectious agents and cancer · 2016Article
- Molecular analysis of human Papillomavirus detected among women positive for cervical lesions by visual inspection with acetic acid/Lugol's iodine (VIA/VILI) in Libreville, Gabon.Infectious agents and cancer · 2016Article
- Specific genotypes of human papillomavirus in 125 high-grade squamous lesions and invasive cervical cancer cases from Congolese women.BMC public health · 2014Article
- Human papillomavirus genotypes in human immunodeficiency virus-positive patients with anal pathology in Madrid, Spain.Diagnostic pathology · 2013Article
- Mesonephric adenocarcinoma with a sarcomatous component, a notable subtype of cervical carcinosarcoma: a case report and review of the literature.Diagnostic pathology · 2013Review
- Upregulation of microRNA-224 is associated with aggressive progression and poor prognosis in human cervical cancer.Diagnostic pathology · 2013Article
- Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe HVP vaccine is a useful tool for preventing cervical cancer. The purpose of this study is to determine the most frequent HPV genotypes in Equatorial Guinea in order to develop future vaccination strategies to apply in this country.
methodsA campaign against cervical cancer was carried out in the area on a total of 1,680 women. 26 of the women, following cytological screening, were treated surgically with a loop electrosurgical excision procedure (LEEP). Cases were studied histologically and were genotyped from paraffin blocks by applying a commercial kit that recognized 35 HPV types.
resultsCytological diagnoses included 17 HSIL, 1 LSIL, 5 ASC-H and 3 AGUS. Histological diagnosis resulted in 3 cases of microinvasive squamous cell carcinoma stage IA of FIGO, 9 CIN-3, 8 CIN-2, 2 CIN-1, 3 flat condylomas and mild dysplasia of the endocervical epithelium. Fifteen of twenty-five cases genotyped were positive for HPV (60%). HPV 16 and 33 were identified in four cases each, HPV 58 in two other cases, and HPV 18, 31, 52, and 82 in one case, with one HPV 16 and 58 coinfection.
conclusionThe frequency of HPV types in the African area varies in comparison to other regions, particularly in Europe and USA. Vaccination against the five most common HPV types (16, 33, 58, 18, and 31) should be considered in the geographic region of West Africa and specifically in Equatorial Guinea.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.