Evidence map›Paper›PMID 19736553›Full record

ReviewNature reviews. Cardiology2009

Imaging myocardial angiogenesis.

Joanna J Wykrzykowska, Timothy D Henry, John R Lesser, Robert S Schwartz

Registry-linked trialAbstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Cardiology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03350737 (Coronary ARteriogenesis With Combined Heparin and EXercise Therapy in Chronic Refractory Angina), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03350737 nacompletednot on this mapstarted 2013, after this paper: background citation

Coronary ARteriogenesis With Combined Heparin and EXercise Therapy in Chronic Refractory Angina

TypeinterventionalSponsorClinical Centre of SerbiaRan2013 to 2019Enrolled32ConditionsRefractory Angina, Chronic Stable AnginaArmsPhysical rehabilitation, Heparin, Placebo
3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. The future of collateral artery research.Current cardiology reviews · 2014
    Review
  2. Article
  3. Review
  4. Review
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Joanna J WykrzykowskaThe Thoraxcenter, Erasmus Medical Centre, Rotterdam, The Netherlands.
Timothy D Henry
John R Lesser
Robert S Schwartz

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Imaging myocardial angiogenesis presents a major technical challenge because the ideal spatial resolution required is substantially higher than that available with standard X-ray angiography and nuclear medicine imaging. Moreover, these clinical imaging methods are currently inadequate (because of insufficient resolution) for clinical trials of angiogenic agents for the treatment of ischemic heart disease. Specialized techniques in MRI, ultrasonography, echocardiography and CT that are under development might provide improved means of imaging myocardial angiogenesis. Molecular imaging technologies are also being developed to improve resolution and to provide a better mechanistic insight into angiogenic therapies for ischemic heart diseases. This Review examines advanced methods for imaging angiogenesis. These technologies might soon permit data to be obtained directly from scientific studies and clinical trials.

Indexed as

Collateral CirculationCoronary CirculationDiagnostic ImagingNeovascularization, PhysiologicAngiogenesis Inducing AgentsAnimalsHumansMyocardial IschemiaMyocardiumPredictive Value of TestsTreatment OutcomeAngiogenesis Inducing Agents

Identifiers

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.